Chemistry:Perfluoroalkyl ether sulfonic acid
From HandWiki
Perfluoroalkyl ether sulfonic acids (abbreviated as PFESAs) refers to compounds with the formula CF
3(CF
2)
mO(CF
2)
nSO
3H. Several are known. These compounds are members of the PFAS class of fluorocarbon-based surfactants. They were invented partly in response to the controversy over the persistence of PFAS.[1] Some PFESAs can be prepared from hexafluoropropylene oxide.[2]
Studies of PFESAs in lab mice have demonstrated comparatively higher hepatotoxicity than PFOS.[3] Industrially, PFESAs are used in chromium plating and as a replacement for other PFAS in fluoropolymer manufacturing.[4]
References
- ↑ Strynar, Mark; Dagnino, Sonia; McMahen, Rebecca; Liang, Shuang; Lindstrom, Andrew; Andersen, Erik; McMillan, Larry; Thurman, Michael et al. (2015). "Identification of Novel Perfluoroalkyl Ether Carboxylic Acids (PFECAs) and Sulfonic Acids (PFESAs) in Natural Waters Using Accurate Mass Time-of-Flight Mass Spectrometry (TOFMS)". Environmental Science & Technology 49 (19): 11622–11630. doi:10.1021/acs.est.5b01215. PMID 26392038. Bibcode: 2015EnST...4911622S.
- ↑ Oppenheimer, Jossian; Hsung, Richard P.; Li, Hongyan; Lu, Ting; Wei, Yonggang (2007). "Hexafluoropropene Oxide". Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289x.rn00768. ISBN 978-0-471-93623-7.
- ↑ Yao, Jingzhi; Pan, Yitao; Sheng, Nan; Su, Zhaoben; Guo, Yong; Wang, Jianshe; Dai, Jiayin (2020-11-03). "Novel Perfluoroalkyl Ether Carboxylic Acids (PFECAs) and Sulfonic Acids (PFESAs): Occurrence and Association with Serum Biochemical Parameters in Residents Living Near a Fluorochemical Plant in China". Environmental Science & Technology 54 (21): 13389–13398. doi:10.1021/acs.est.0c02888.
- ↑ Zhang, Chuhui; Hopkins, Zachary R.; McCord, James; Strynar, Mark J.; Knappe, Detlef R. U. (2019). "Fate of Per- and Polyfluoroalkyl Ether Acids in the Total Oxidizable Precursor Assay and Implications for the Analysis of Impacted Water". Environmental Science & Technology Letters 6 (11): 662–668. doi:10.1021/acs.estlett.9b00525. PMID 31909080.
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