Chemistry:Retinyl acetate

Retinyl acetate

Names
IUPAC name (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
Other names Retinol acetate; Vitamin A acetate; Vitamin A1 acetate; Acetylretinol; all-trans-Retinol acetate; all-trans-Retinyl acetate; all-trans-Vitamin A acetate;
Identifiers
CAS Number	127-47-9 Y
3D model (JSmol)	Interactive image
Beilstein Reference	1915439
ChEBI	CHEBI:32095
ChEMBL	ChEMBL486193
ChemSpider	553599
EC Number	204-844-2
KEGG	D01621
PubChem CID	638034
UNII	3LE3D9D6OY Y
InChI InChI=1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+ Key: QGNJRVVDBSJHIZ-QHLGVNSISA-N InChI=1/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+ Key: QGNJRVVDBSJHIZ-QHLGVNSIBE
SMILES O=C(OC/C=C(/C=C/C=C(/C=C/C1=C(/CCCC1(C)C)C)C)C)C
Properties
Chemical formula	C22H32O2
Molar mass	328.496 g·mol−1
Melting point	57 to 58 °C (135 to 136 °F; 330 to 331 K)
Hazards
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H315, H361, H413
GHS precautionary statements	P201, P202, P264, P273, P280, P281, P302+352, P308+313, P321, P332+313, P362, P405, P501
NFPA 704 (fire diamond)	1 1 0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tracking categories (test):

• SizeSet

Retinyl acetate (retinol acetate, vitamin A acetate) is a natural form of vitamin A which is the acetate ester of retinol. It has potential antineoplastic and chemopreventive activities.

In the United States, retinyl acetate is classified generally recognized as safe (GRAS) in the amounts used to fortify foods with vitamin A.

Toxicology

World Health Organization "Recommendations for preformed vitamin A supplements for mothers during pregnancy" states that "health benefits are expected for the mother and her developing fetus with little risk of detriment to either, from a daily supplement not exceeding 10,000 IU vitamin A (3000mcg RE) at any time during pregnancy." Preformed Vitamin A refers to retinol and retinyl esters, such as retinyl palmitate and retinyl acetate.