Chemistry:Ronidazole

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Ronidazole
Ronidazole Structural Formula V.1.svg
Names
Preferred IUPAC name
(1-Methyl-5-nitro-1H-imidazol-2-yl)methyl carbamate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
Properties
C6H8N4O4
Molar mass 200.154 g·mol−1
Pharmacology
1=ATCvet code} QP51CA02 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Ronidazole is an antiprotozoal agent used in veterinary medicine for the treatment of histomoniasis and swine dysentery[1][2] as well as Trichomonas gallinae, hexamitosis, Giardia, and Cochlosoma in all aviary birds and pigeons.[3] It may also have use for the treatment of Tritrichomonas foetus infection in cats[4][5][6] and for the treatment of Clostridioides difficile infection in humans.[7]

References

  1. Sullivan, T.W.; Grace, O.D.; Aksoy, Ayhan (1977-03-01). "Influence of Level, Timing and Duration of Ronidazole Water Medication on Histomoniasis in Turkeys1". Poultry Science 56 (2): 571–576. doi:10.3382/ps.0560571. ISSN 0032-5791. PMID 564505. 
  2. Olson, L. D.; Rodabaugh, D. E. (July 1976). "Ronidazole in low concentrations in drinking water for treatment and development of immunity to swine dysentery.". American Journal of Veterinary Research 37 (7): 763–767. ISSN 0002-9645. PMID 937800. https://pubmed.ncbi.nlm.nih.gov/937800/. Retrieved 2022-03-17. 
  3. "Ronidazole" (in en). https://allbirdproducts.com/products/ronidazole. 
  4. Gunn-Moore, Danielle; Lalor, Stephanie (2011-01-01). "Treatment of diarrhoea in cats caused by Tritrichomonas foetus". Veterinary Record 168 (2): 56–57. doi:10.1136/vr.d189. ISSN 0042-4900. PMID 21257565. https://bvajournals.onlinelibrary.wiley.com/doi/abs/10.1136/vr.d189. Retrieved 2022-03-17. 
  5. "Tritrichomonas foetus infection in cats and treatment with RONIDAZOLE" (in en). December 2009. https://www.ed.ac.uk/files/imports/fileManager/Ronidazole%20treatment%20sheet%20for%20vets%20-%202009.pdf. 
  6. Davidson, Gigi S. (December 2006). "Ronidazole in the treatment of trichomonad infections in cats.". International Journal of Pharmaceutical Compounding 10 (6): 434–435. ISSN 1092-4221. PMID 23974416. https://pubmed.ncbi.nlm.nih.gov/23974416/. Retrieved 2022-03-17. 
  7. AbdelKhalek, Ahmed; Seleem, Mohamed N. (December 2020). "Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides difficile Infection". International Journal of Antimicrobial Agents 56 (6): 106188. doi:10.1016/j.ijantimicag.2020.106188. ISSN 1872-7913. PMID 33045352.