Chemistry:SBI-797812
From HandWiki
SBI-797812, is a drug which acts as a selective activator of the enzyme nicotinamide phosphoribosyltransferase (NAMPT). It increases the rate of nicotinamide mononucleotide production by NAMPT and decreases feedback inhibition by NAD+. It has been researched for application as a potential anti-aging drug.[1][2]
See also
- C8 (NAMPT activator)
References
- ↑ "Boosting NAD+ with a small molecule that activates NAMPT". Nature Communications 10 (1). July 2019. doi:10.1038/s41467-019-11078-z. PMID 31324777. Bibcode: 2019NatCo..10.3241G.
- ↑ "Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process". International Journal of Molecular Sciences 22 (7): 3709. April 2021. doi:10.3390/ijms22073709. PMID 33918226.
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