Chemistry:SCH-202,596

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Short description: Chemical compound
SCH-202,596
SCH-202,596.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
Chemical and physical data
FormulaC25H22Cl2O12
Molar mass585.34 g·mol−1
3D model (JSmol)

SCH-202,596 is a natural product which is a metabolite derived from an Aspergillus fungus. It acts as a selective non-peptide antagonist for the receptor GAL-1, which is usually activated by the neuropeptide galanin. SCH-202,596 is used for scientific research into this still little characterised receptor subtype.[1][2]

References

  1. "A new fungal metabolite, Sch 202596, with inhibitory activity in the galanin receptor GALR1 assay.". Tetrahedron Letters 38 (35): 6111–4. September 1997. doi:10.1016/S0040-4039(97)01385-3. 
  2. "Synthetic studies on Sch 202596, an antagonist of the galanin receptor subtype GalR1: an efficient synthesis of (±)-geodin, the spirocoumaranone part of Sch 202596.". Tetrahedron 58 (7): 1289–99. February 2002. doi:10.1016/S0040-4020(01)01250-9.