Chemistry:Suplatast tosilate
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Short description: Chemical compound
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| Routes of administration | Oral |
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| Formula | C23H33NO7S2 |
| Molar mass | 499.64 g·mol−1 |
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Suplatast tosilate (INN) is a Th2 cytokine inhibitor[1] which is used as an antihistamine. It has been suggested and applied in the treatment of Kimura's disease a few times.[2][3]
References
- ↑ "Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group". Lancet 356 (9226): 273–8. July 2000. doi:10.1016/S0140-6736(00)02501-0. PMID 11071181.
- ↑ "Kimura's disease treated with suplatast tosilate and loratadine". European Journal of Dermatology 21 (6): 1020–1. 2011. doi:10.1684/ejd.2011.1539. PMID 21914581.
- ↑ "Kimura's disease associated with bronchial asthma presenting eosinophilia and hyperimmunoglobulinemia E which were attenuated by suplatast tosilate (IPD-1151T)". Internal Medicine 37 (12): 1064–7. December 1998. doi:10.2169/internalmedicine.37.1064. PMID 9932643.
Further reading
- "Suplatast tosilate, a new type of antiallergic agent, prevents the expression of airway hyperresponsiveness in guinea pigs". European Journal of Pharmacology 318 (2–3): 447–54. December 1996. doi:10.1016/S0014-2999(96)00810-2. PMID 9016937.
- Sano Y (December 1996). "[Anti-inflammatory drugs for the treatment of bronchial hyperresponsiveness]" (in ja). Nihon Kyōbu Shikkan Gakkai Zasshi 34 Suppl: 48–53. PMID 9216184.
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