Chemistry:Vermistatin
From HandWiki
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| Names | |
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| Preferred IUPAC name
(3R)-4,6-Dimethoxy-3-{4-oxo-6-[(1E)-prop-1-en-1-yl]-4H-pyran-3-yl}-2-benzofuran-1(3H)-one | |
| Other names
5-(4,6-Dimethoxyphthalidyl)-2-propenyl-4H-pyran-4-one
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| Identifiers | |
3D model (JSmol)
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| ChEMBL | |
| ChemSpider | |
PubChem CID
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| UNII | |
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| Properties | |
| C18H16O6 | |
| Molar mass | 328.320 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Vermistatin is an organic compound and a metabolite of mine-dwelling Penicillium vermiculatum found in Berkeley Pit Lake, Butte, Montana.[1] Penisimplicissin is a vermistatin analog with anticancer activity.[2]
References
- ↑ Fuska, J; Uhrín, D; Proksa, B; Votický, Z; Ruppeldt, J (1986). "The structure of vermistatin, a new metabolite from Penicillium vermiculatum". The Journal of Antibiotics 39 (11): 1605–8. doi:10.7164/antibiotics.39.1605. PMID 3793630.
- ↑ "Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell lines.". J Nat Prod 75 (3): 344–50. 2012. doi:10.1021/np200414c. PMID 22295871.
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