Medicine:Glomerulopathy
| Glomerulopathy |
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Glomerulopathy is diseases that impact the glomeruli in the nephron, either inflammatory or noninflammatory.[1] Glomerulopathy includes collapsing glomerulopathy, glomerulocystic kidney disease, glomerulomegaly, membranous nephropathy, and tip lesion glomerulopathy.[2]
Collapsing glomerulopathy (CG) is a clinicopathologic entity that involves hypertrophy and hyperplasia of podocytes and segmentar or global collapse of the glomerulus.[3]
Glomerulocystic kidney disease is a rare form of renal cyst disease. Cortical microcysts, which are portrayed by cystic dilatation of Bowman's spaces, are its defining feature.[4]
Glomerulomegaly is defined by unusually large glomeruli.[5]
Membranous nephropathy (MN) is an uncommon autoimmune condition in which autoantibodies directed primarily against podocyte antigens target the glomerulus, causing electron-dense immune complexes to form, complement activation to occur, and severe proteinuria.[6]
The glomerular tip lesion (GTL) is a unique histopathologic lesion that appears in idiopathic nephrotic syndrome patients.[7]
See also
- Glomerulonephritis
- Glomerulonephrosis
References
- ↑ "Monarch Initiative". https://monarchinitiative.org/HP:0100820.
- ↑ "Glomerulopathy (Concept Id: C0268731)". October 31, 2023. https://www.ncbi.nlm.nih.gov/medgen/451033.
- ↑ Cutrim, Érico Murilo Monteiro; Neves, Precil Diego Miranda de Meneses; Campos, Marcos Adriano Garcia; Wanderley, Davi Campos; Teixeira-Júnior, Antonio Augusto Lima; Muniz, Monique Pereira Rêgo; Ladchumananandasivam, Francisco Rasiah; Gomes, Orlando Vieira et al. (March 3, 2022). "Collapsing Glomerulopathy: A Review by the Collapsing Brazilian Consortium". Frontiers in Medicine (Frontiers Media SA) 9. doi:10.3389/fmed.2022.846173. ISSN 2296-858X. PMID 35308512.
- ↑ Sahay, M.; Gowrishankar, S. (April 13, 2010). "Glomerulocystic disease". Clinical Kidney Journal (Oxford University Press (OUP)) 3 (4): 349–350. doi:10.1093/ndtplus/sfq048. ISSN 2048-8505. PMID 25949428.
- ↑ Hughson, M. D.; Hoy, W. E.; Douglas-Denton, R. N.; Zimanyi, M. A.; Bertram, J. F. (November 29, 2010). "Towards a definition of glomerulomegaly: clinical-pathological and methodological considerations". Nephrology Dialysis Transplantation (Oxford University Press (OUP)) 26 (7): 2202–2208. doi:10.1093/ndt/gfq688. ISSN 0931-0509. PMID 21115671.
- ↑ Ronco, Pierre; Plaisier, Emmanuelle; Debiec, Hanna (February 5, 2021). "Advances in Membranous Nephropathy". Journal of Clinical Medicine (MDPI AG) 10 (4): 607. doi:10.3390/jcm10040607. ISSN 2077-0383.
- ↑ Stokes, M. Barry; Markowitz, Glen S.; Lin, Julie; Valeri, Anthony M.; D'Agati, Vivette D. (2004). "Glomerular tip lesion: A distinct entity within the minimal change disease/focal segmental glomerulosclerosis spectrum". Kidney International (Elsevier BV) 65 (5): 1690–1702. doi:10.1111/j.1523-1755.2004.00563.x. ISSN 0085-2538. PMID 15086908.
Further reading
- Couser, William G. (May 26, 2017). "Primary Membranous Nephropathy". Clinical Journal of the American Society of Nephrology (Ovid Technologies (Wolters Kluwer Health)) 12 (6): 983–997. doi:10.2215/cjn.11761116. ISSN 1555-9041. PMID 28550082.
- Ronco, Pierre; Beck, Laurence; Debiec, Hanna; Fervenza, Fernando C.; Hou, Fan Fan; Jha, Vivekanand; Sethi, Sanjeev; Tong, Allison et al. (September 30, 2021). "Membranous nephropathy". Nature Reviews Disease Primers (Springer Science and Business Media LLC) 7 (1). doi:10.1038/s41572-021-00303-z. ISSN 2056-676X. PMID 34593809.
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