Medicine:H antigen
From HandWiki
Short description: Antigens with different biological functions
H antigen can refer to one of the various types of antigens having diverse biological functions:
- Also known as substance H, H antigen is a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype[1] (see hh blood group). The gene responsible for making H antigen is FUT1, located on the 19th chromosome in humans.
- Histocompatibility antigen, a major factor in graft rejection.
- major H antigens (major histocompatibility antigen[2]) "encode molecules that present foreign peptides to T cells"[3][page needed]
- minor H antigens are polymorphic alloantigens presented on foreign major histocompatibility complex molecules.[3]: 525–526 Includes, e.g. the H-Y antigen. Even when major histocompatibility complex genotype is perfectly matched, can cause slow rejection of a graft.[3]: 525–526
- a bacterial flagellar antigen[4]
References
- ↑ Science Of Biogenetics (18 December 2023). "Do you Know Bombay Blood Group". http://www.scienceofbiogenetics.com/do-you-know-bombay-blood-group/.
- ↑ Doherty, P.C.; Zinkernagel, R.M. (1975). "A Biological Role for the Major Histocompatibility Antigens". The Lancet 305 (7922): 1406-1609. doi:10.1016/s0140-6736(75)92610-0. PMID 49564.
- ↑ 3.0 3.1 3.2 Janeway, Charles A. (2001). Immunobiology the immune system health & disease (5. ed.). New York: Garland. ISBN 978-0-8153-3642-6. https://archive.org/details/immunobiology00char. Retrieved 16 December 2013.
- ↑ Farlex. "antigen". The Free Dictionary. http://medical-dictionary.thefreedictionary.com/antigen. Retrieved 16 December 2013.
 |  |
