Medicine:Hepatoprotection
From HandWiki
Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity.
Hepatoprotective molecules used in emergency medicine
- Acetylcysteine is considered the hepatoprotective drug of choice when treating an overdose of acetaminophen/paracetamol.[1]
- Silymarin is given intravenously to treat poisoning from Amanita mushrooms according to the Santa Cruz protocol devised by Dr Todd Mitchell at UCSC.
Herbs with potentially hepatoprotective constituents
- Astragalus membranaceus[2]
- Curcuma longa[3]
- Brassica[4]
- Silybum marianum
- Andrographis paniculata[5]
References
- ↑ "Archived copy". https://poisoncontrol.utah.edu/newsletters/pdfs/toxicology-today-archive/Vol7_No1.pdf.
- ↑ Chien, CF; Wu, YT; Tsai, TH (Jan 2011). "Biological analysis of herbal medicines used for the treatment of liver diseases.". Biomedical Chromatography 25 (1–2): 21–38. doi:10.1002/bmc.1568. PMID 21204110.
- ↑ Ghosh, N; Ghosh, R; Mandal, V; Mandal, SC (Sep 2011). "Recent advances in herbal medicine for treatment of liver diseases.". Pharmaceutical Biology 49 (9): 970–88. doi:10.3109/13880209.2011.558515. PMID 21595500.
- ↑ Steinkellner, H; Rabot, S; Freywald, C; Nobis, E; Scharf, G; Chabicovsky, M; Knasmüller, S; Kassie, F (Sep 1, 2001). "Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.". Mutation Research 480-481: 285–97. doi:10.1016/S0027-5107(01)00188-9. PMID 11506821.
- ↑ Andrographis paniculata http://www.stuartxchange.com/Sinta.html
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