Medicine:Lelis syndrome
From HandWiki
| Lelis syndrome | |
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| Other names | Ectodermal dysplasia-acanthosis nigricans syndrome |
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| This condition is inherited in an autosomal recessive manner. | |
Lelis syndrome is a genetic disorder, a rare condition with dermatological and dental findings[1] characterized by the association of ectodermal dysplasia (hypotrichosis and hypohidrosis) with acanthosis nigricans. Other clinical features may include palmoplantar hyperkeratosis, nail dystrophy, intellectual deficit,[2] disturbances of skin pigmentation (perioral and periorbital hyperpigmentation, vitiligo, and perinevic leukoderma)[2] and hypodontia. Transmission is autosomal recessive.[1][3]
See also
- List of cutaneous conditions
References
- ↑ 1.0 1.1 Samdani AJ (October 2004). "Ectodermal dysplasia with acanthosis nigricans (Lelis' syndrome)". J Coll Physicians Surg Pak 14 (10): 626–7. PMID 15456556.
- ↑ 2.0 2.1 Lelis J (June 1992). "Autosomal recessive ectodermal dysplasia". Cutis 49 (6): 435–7. PMID 1628512.
- ↑ "Ectodermal dysplasia with acanthosis nigricans (Lelis syndrome)". Am. J. Med. Genet. 113 (4): 381–4. December 2002. doi:10.1002/ajmg.b.10787. PMID 12457412.
External links
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