Medicine:Parsonage–Turner syndrome

From HandWiki
Parsonage–Turner syndrome
Other namesacute brachial radiculitis,[1] Parsonage–Aldren–Turner syndrome', neuralgic amyotrophy,[2] brachial neuritis, brachial plexus neuropathy,[3] brachial plexitis, acute brachial neuropathy
Gray808.png
The right brachial plexus with its short branches, viewed from in front.

Parsonage–Turner syndrome, also known as acute brachial neuropathy, neuralgic amyotrophy and abbreviated PTS, is a syndrome of unknown cause; although many specific risk factors have been identified (such as; post-operative, post-infectious, post-traumatic or post-vaccination),[4] the cause is still unknown. The condition manifests as a set of symptoms most likely resulting from autoimmune inflammation of unknown cause of the brachial plexus.[5]

Parsonage–Turner syndrome occurs in about 1.6 out of 100,000 people every year.[6]

Signs and symptoms

This syndrome can begin with severe shoulder or arm pain followed by weakness and numbness.[5] Those with Parsonage–Turner experience acute, sudden-onset pain radiating from the shoulder to the upper arm. Affected muscles become weak and atrophied, and in advanced cases, paralyzed. Occasionally, there will be no pain and just paralysis, and sometimes just pain, not ending in paralysis.[citation needed] MRI may assist in diagnosis.[7] Scapular winging is commonly seen.

Mechanism

Parsonage-Turner involves neuropathy of the suprascapular nerve in 97% of cases, and variably involves the axillary and subscapular nerves. As such, the muscles usually involved are the supraspinatus and infraspinatus, which are both innervated by the suprascapular nerve. Involvement of the deltoid is more variable, as it is innervated by the axillary nerve.[8]

Diagnosis

Diagnosis often takes three to nine months to be made, as the condition is often unrecognised by physicians.[9]

Differential diagnosis

The differential focuses on distinguishing it from similar entities such as quadrilateral space syndrome, which involves the teres minor and variably the deltoid, and suprascapular nerve impingement at the spinoglenoid notch, which predominantly involves the infraspinatus.[8]

Prognosis

Despite its wasting and at times long-lasting effects, most cases are resolved by the body's healing system, and recovery is usually good in 18–24 months, depending on how old the person in question is. For instance, a six-year-old could have brachial neuritis for only around six months, but a person in their early 50s could have it for more than three years.[citation needed]

It was traditionally thought that most people would regain around 70-90 per cent of their original strength and function levels,[10] however most recent studies suggest that long-term complications are more common than previously thought.[11]

Eponym

It is named after British neurologists Maurice Parsonage and John Turner,[12][13] who described 136 cases in a 1948 Lancet publication.[14][4] Other cases with similar symptom presentation had previously been published as early as 1897, but these publications were not as extensive as Parsonage and Turner's 1948 publication.[4]

See also

References

  1. ↑ Wheeless, Clifford R. (30 August 2009). "Parsonage-Turner Syndrome". Wheeless' Textbook of Orthopedics @ wheelessonline.com. http://www.wheelessonline.com/ortho/parsonage_turner_syndrome. 
  2. ↑ Cary D. Alberstone; Michael Steinmetz; Edward C. Benzel (28 January 2009). Anatomic Basis of Neurologic Diagnosis. Thieme. pp. 105–. ISBN 978-0-86577-976-1. https://books.google.com/books?id=7VG1om3OmyUC&pg=PA105. Retrieved 4 November 2010. 
  3. ↑ Charles A. Rockwood (14 January 2009). The Shoulder. Elsevier Health Sciences. pp. 1376–. ISBN 978-1-4160-3427-8. https://books.google.com/books?id=7ca8iqAPo2UC&pg=PA1376. Retrieved 4 November 2010. 
  4. ↑ 4.0 4.1 4.2 "Parsonage-turner syndrome". HSS J 6 (2): 199–205. 2010. doi:10.1007/s11420-010-9176-x. PMID 21886536. 
  5. ↑ 5.0 5.1 "NINDS Brachial Plexus Injuries: Information Page". National Institute of Neurological Disorders and Stroke. September 29, 2008. http://www.ninds.nih.gov/disorders/brachial_plexus/brachial_plexus.htm. 
  6. ↑ "Brachial plexus neuropathy in the population of Rochester, Minnesota, 1970-1981". Ann. Neurol. 18 (3): 320–3. 1985. doi:10.1002/ana.410180308. PMID 2996415. 
  7. ↑ William E. Brant; Clyde A. Helms (2007). Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins. pp. 1–. ISBN 978-0-7817-6135-2. https://books.google.com/books?id=Sossht2t5XwC&pg=RA1-PA1213. Retrieved 4 November 2010. 
  8. ↑ 8.0 8.1 Frank Gaillard MD. "Parsonage-Turner syndrome". Radiopaedia. http://radiopaedia.org/articles/parsonage-turner-syndrome-1. 
  9. ↑ van Alfen, Nens; van Engelen, Baziel GM; Hughes, Richard AC (23 January 2008). Van Alfen, Nens. ed. "Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis)". Cochrane Database of Systematic Reviews (Chichester, UK: John Wiley & Sons, Ltd). doi:10.1002/14651858.cd006976. http://dx.doi.org/10.1002/14651858.cd006976. 
  10. ↑ "Parsonage Turner Syndrome". National Organization for Rare Disorders. https://rarediseases.org/rare-diseases/parsonage-turner-syndrome/. 
  11. ↑ "Parsonage Turner syndrome". Genetic and Rare Diseases Information Center. National Center for Advancing Translational Sciences. https://rarediseases.info.nih.gov/diseases/4228/parsonage-turner-syndrome. 
  12. ↑ synd/1910 at Who Named It?
  13. ↑ "Neuralgic amyotrophy; the shoulder-girdle syndrome". Lancet 1 (6513): 973–8. June 1948. doi:10.1016/S0140-6736(48)90611-4. PMID 18866299. 
  14. ↑ Sanders, Lisa (19 November 2020). "He Finished His First Marathon. Then His Arm Felt Weak.". The New York Times. https://www.nytimes.com/2020/11/19/magazine/parsonage-turner-syndrome.html. 

External links

Classification



Retrieved from "https://handwiki.org/wiki/index.php?title=Medicine:Parsonage–Turner_syndrome&oldid=3273399"