Software:Eyewire

From HandWiki
Short description: Human-based computation game
Eyewire
EyeWire-Logo-Blue.png
Developer(s)Sebastian Seung of Princeton University (formerly Massachusetts Institute of Technology)
Director(s)Amy Sterling
Platform(s)Webbrowser (WebGL)
ReleaseDecember 10, 2012
Genre(s)Puzzle, Citizen Science

Eyewire is a citizen science game from Sebastian Seung's Lab at Princeton University. It is a human-based computation game that uses players to map retinal neurons. Eyewire launched on December 10, 2012. The game utilizes data generated by the Max Planck Institute for Medical Research.[1]

Eyewire gameplay is used for neuroscience research by enabling the reconstruction of morphological neuron data, which helps researchers model information-processing circuits.[2][3]

Gameplay

The player is given a cube with a partially reconstructed neuron branch stretching through it. The player completes the reconstruction by coloring a 2D image with a 3D image generated simultaneously. Reconstructions are compared across players as each cube is submitted, yielding a consensus reconstruction that is later checked by experienced players.

Goal

Eyewire is used to advance the use of artificial intelligence in neuronal reconstruction.[4] The project is also used in research determining how mammals see directional motion.[5][6]

Methods

The activity of each neuron in a 350 × 300 × 60 μm3 portion of a retina was determined by two-photon microscopy.[7] Using serial block-face scanning electron microscopy, the same volume was stained to bring out the contrast of the plasma membranes, sliced into layers by a microtome, and imaged using an electron microscope.

A neuron is selected by the researchers. The program chooses a cubic volume associated with that neuron for the player, along with an artificial intelligence's best guess for tracing the neuron through the two-dimensional images.[8]

Publications

Accomplishments

  • Eyewire neurons featured at 2014 TED Conference Virtual Reality Exhibit.[9][10]
  • Eyewire neurons featured at US Science and Engineering Expo in Washington, DC.[11]
  • Eyewire won the National Science Foundation's 2013 International Visualization Challenge in the Games and Apps Category.[12]
  • An Eyewire image by Alex Norton won MIT's 2014 Koch Image Gallery Competition.[13]
  • Eyewire named one of Discover Magazine's Top 100 Science Stories of 2013.[14]
  • Eyewire named top citizen science project of 2013 by SciStarter.[15]
  • Eyewire won Biovision's World Life Sciences Forum Catalyzer Prize on March 26, 2013.[16]
  • Eyewire named to top 10 citizen science projects of 2013 by PLoS.[17]

Eyewire has been featured by Wired,[18] Nature's blog SpotOn,[19] Forbes ,[20] Scientific American,[21] and NPR.[22]

References

  1. "About << Eyewire". http://eyewire.org/about/. 
  2. Kim, Jinseop S; Greene, Matthew J; Zlateski, Aleksandar; Lee, Kisuk; Richardson, Mark; Turaga, Srinivas C; Purcaro, Michael; Balkam, Matthew et al. (2014). "Space–time wiring specificity supports direction selectivity in the retina". Nature 509 (7500): 331–336. doi:10.1038/nature13240. PMID 24805243. Bibcode2014Natur.509..331.. 
  3. Tinati, Ramine; Luczak-Roesch, Markus; Simperl, Elena; Shadbolt, Nigel; Hall, Wendy (2015). "'/Command' and Conquer: Analysing Discussion in a Citizen Science Game". Proceedings of the ACM Web Science Conference on ZZZ - Web Sci '15. p. 26. doi:10.1145/2786451.2786455. ISBN 978-1-4503-3672-7. https://eprints.soton.ac.uk/377766/1/2015___WebScience___EyeWire__Quant_.pdf. 
  4. "Neural networks: Theory and Applications". http://seunglab.org/courses/neuralnets15/. 
  5. "Retina << Eyewire". http://eyewire.org/retina. 
  6. "Eyewire". http://eyewire.org/. 
  7. "Challenge << Eyewire". http://eyewire.org/challenge/. 
  8. Sebastian Seung (March 18, 2012). "Very small sections of neuron". http://forum.eyewire.org/discussion/8/very-small-sections-of-neuron-#Item_11. "A few more words of explanation for the curious...you color neurons on Eyewire by guiding an artificial intelligence (AI). The AI was trained to color the branches of neurons." 
  9. "At TED, Worldwide Telescope uses Oculus Rift to let attendees experience the universe - Next at Microsoft - Site Home - TechNet Blogs". http://blogs.technet.com/b/next/archive/2014/03/19/at-ted-worldwide-telescope-uses-oculus-rift-to-let-attendees-experience-the-universe.aspx#.U1AjneZdXKg. 
  10. "Yes, that's Commander Chris Hadfield wearing the Oculus Rift. (And yes, the Internet just exploded.)". 26 March 2014. http://blog.ted.com/2014/03/25/yes-thats-commander-chris-hadfield-wearing-the-oculus-rift-and-yes-the-internet-just-exploded/. 
  11. "USA Science & Engineering Festival - The Nation's Largest Science Festival". http://www.usasciencefestival.org/. 
  12. "Science: 2013 International Science and Engineering Visualization Challenge Winners Announced". 5 February 2014. http://www.aaas.org/news/science-2013-international-science-and-engineering-visualization-challenge-winners-announced. 
  13. "Koch2014winners: Cell Press". http://www.cell.com/pictureshow/koch2014winners. 
  14. "Science For the People, By the People". http://discovermagazine.com/2014/jan-feb/76-science-for-the-people-by-the-people. 
  15. "Top 13 Citizen Science Projects of 2013". 1 January 2014. http://scistarter.com/blog/2014/01/top-13-citizen-science-projects-2013/#sthash.Rz9YzHim.dpbs. 
  16. "BIOVISION Catalyzer". http://www.biovision.org/focus2-catalyzer.html. 
  17. "Top Citizen Science Projects of 2012 - CitizenSci". 31 December 2012. http://blogs.plos.org/citizensci/2012/12/31/top-citizen-science-projects-of-2012/. 
  18. Stinson, Liz (2 August 2013). "A Videogame That Recruits Players to Map the Brain". Wired. https://www.wired.com/2013/08/a-video-game-that-lets-you-be-a-neuroscientist/. Retrieved 10 November 2019. 
  19. SpotOn Editor (14 March 2013). "SpotOn NYC: Communication and the brain – A Game to Map the Brain". Nature. http://www.nature.com/spoton/2013/03/spoton-nyc-communication-and-the-brain-a-game-to-map-the-brain/. 
  20. Frank, Aaron; with Vivek Wadhwa (19 August 2013). "70,000+ Have Played 'Eyewire' Game That Trains Computers to Map the Brain". Forbes. https://www.forbes.com/sites/singularity/2013/08/19/70000-have-played-eyewire-game-that-trains-computers-to-map-the-brain/. Retrieved 10 November 2019. 
  21. "Update: EyeWire". Scientific American. 13 June 2014. http://www.scientificamerican.com/citizen-science/update-eyewire-mit/. Retrieved April 17, 2014. 
  22. Palca, Joe (5 March 2013). "Wanna Play? Computer Gamers Help Push Frontier of Brain Research". Morning Edition (NPR). https://www.npr.org/2013/03/05/173435599/wanna-play-computer-gamers-help-push-frontier-of-brain-research. 

External links