Software:Staden Package
Original author(s) | Rodger Staden |
---|---|
Developer(s) | James Bonfield, et al. |
Initial release | 1977 |
Stable release | 2.0.0b9
/ 24 January 2012 |
Preview release | 2.0.0b11
/ 25 April 2016 |
Repository | sourceforge |
Written in | C, C++, Fortran, Tcl |
Operating system | Unix, Linux, macOS, Windows |
Platform | IA-32, x86-64 |
Available in | English |
Type | Bioinformatics |
License | BSD 3-clause |
Website | staden |
The Staden Package is computer software, a set of tools for DNA sequence assembly, editing, and sequence analysis. It is open-source software, released under a BSD 3-clause license.
Package components
The Staden package consists of several different programs. The main components are:
- pregap4 – base calling with Phred, end clipping, and vector trimming
- trev – trace viewing and editing
- gap4 – sequence assembly, contig editing, and finishing
- gap5 – assembly visualising, editing, and finishing of NGS data[1]
- Spin – DNA and protein sequence analysis
History
The Staden Package was developed by Rodger Staden's group at the Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, England, since 1977.[2][3][4] The package was available free to academic users, with 2,500 licenses issued in 2003 and an estimated 10,000 users, when funding for further development ended.[5] The package was converted to open source in 2004, and several new versions have been released since.
During the years of active development, the Staden group published a number of widely used file formats and ideas, including the SCF file format,[6] the use of sequence quality scores to generate accurate consensus sequences,[7] and the ZTR file format.[8]
See also
- Genome Compiler
- Phred base calling
- Phrap
- Consed
- CodonCode Aligner
- MacVector
- UGENE
- Vector NTI
References
- ↑ "Gap5—editing the billion fragment sequence assembly". Bioinformatics 26 (14): 1699–1703. 2010. doi:10.1093/bioinformatics/btq268. PMID 20513662.
- ↑ Staden R (1979). "A strategy of DNA sequencing employing computer programs.". Nucleic Acids Res 6 (7): 2601–2610. doi:10.1093/nar/6.7.2601. PMID 461197.
- ↑ Staden R (1984). "Computer methods to aid the determination and analysis of DNA sequences.". Biochem Soc Trans 12 (6): 1005–1008. doi:10.1042/bst0121005. PMID 6397374.
- ↑ "The Staden package, 1998.". Methods Mol Biol 132: 115–130. 2000. doi:10.1385/1-59259-192-2:115. PMID 10547834.
- ↑ "UK s MRC Ends Support for Staden Package: First Sign of Post-HGP Funding Priority Shift?". Genomeweb LLC. 5 May 2003. http://www.genomeweb.com/informatics/uk-s-mrc-ends-support-staden-package-first-sign-post-hgp-funding-priority-shift.
- ↑ "A standard file format for data from DNA sequencing instruments.". DNA Seq 3 (2): 107–110. 1992. doi:10.3109/10425179209034003. PMID 1457811.
- ↑ "The application of numerical estimates of base calling accuracy to DNA sequencing projects.". Nucleic Acids Res 23: 1406–1410. 1995. doi:10.1093/nar/23.8.1406. PMID 7753633.
- ↑ "ZTR: a new format for DNA sequence trace data.". Bioinformatics 18: 3–10. 2002. doi:10.1093/bioinformatics/18.1.3. PMID 11836205.
External links
Original source: https://en.wikipedia.org/wiki/Staden Package.
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