Unsolved:Timeblock

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Short description: Research project


Timeblock is a research project that was developed in Switzerland to discover blue zones and aging-process solutions.[1]

History and origins

The project Timeblock began as a research project by a group of scientists from the Swiss Bluezones Research Group.[2] The term "blue zones" was created by Dr. Michel Poulain and his colleague Giovanni Mario Pes, who discovered the first blue zone in Italy: an area in which an above average number of people live to be 100 years old or older.[3][4][5]

In 1997, the Swiss Research Group started investigating lifestyles, diets and living environments in blue zones (mainly in Japan and Switzerland). Their first focus was the small village Yuzurihara. In 2007, they started to analyse 108 special species of plants for their cancer-fighting and anti-aging properties. In 2014, the Bluezones Research Group and the University of Vienna investigated secondary plant substances from blue zone regions (mainly Tibet and Nepal-Himalayas) growing in remote areas and high altitudes to show that Timeblock can slow down cell rejuvenation by lengthening telomeres 17%.[6][7]

Timeblock has two main product lines: Nutrition Care (Nutraceuticals) and Facial Care (Cosmeceuticals), which is claimed to remodel a person's epigenome in order to optimize the individual DNA.[8][9] Their Nutraceuticals capsules are vegan, non-GMO, gluten-free, lactose-free, and free from chemical preservatives made of plants such as barley grass, green tea (epigallocatechin gallate), wheatgrass, shiitake mushrooms (vitamin D), marigold (zeaxanthin and lutein), grape seeds (flavonoids), tomatoes (lycopene), brown algae (omega-3).[10][11] Cosmeceuticals lotion contains equol, IGF-1 and EGF (insulin-like growth factor and epidermal growth factor), epigallocatechin gallate, microalgae extract and Âmeflore essential oils to promote cell renewal and regeneration to counteract the signs of aging.[12][13]

The active substance in Timeblock Skin Care is equol. The topical effect of equol as an anti-aging and skin health improving substance was shown in different studies. Equol can occur as different isomers: R-equol, S-equol and RS-equol. Each of these forms has different characteristics, bioavailabilities and molecular effects.[14] As an antioxidative operating substance, equol can decrease the aging process by reducing ROS events. Additionally, the phytoestrogenic properties positively influence the skin health.[15]

Awards

In 2019, TimeBlock won Global Health and Travel Awards "Product of the Year" award.[16]

See also

References

  1. ↑ "Direkt vom Hersteller TimeBlock Anti-Aging Kapseln" (in de-DE). https://www.time-block.com/. 
  2. ↑ rcastro05 (2020-10-07). "Renowned Swiss Beauty Brand, "timeblock," Launches in the U.S." (in en). https://www.miamilivingmagazine.com//post/timeblock-swiss-brand-us-launch. 
  3. ↑ Poulain, Michel; Pes, Giovanni Mario; Grasland, Claude; Carru, Ciriaco; Ferrucci, Luigi; Baggio, Giovannella; Franceschi, Claudio; Deiana, Luca (2004). "Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study". Experimental Gerontology 39 (9): 1423–1429. doi:10.1016/j.exger.2004.06.016. ISSN 0531-5565. PMID 15489066. http://dx.doi.org/10.1016/j.exger.2004.06.016. 
  4. ↑ Deiana, L.; Ferrucci, L.; Pes, G. M.; Carru, C.; Delitala, G.; Ganau, A.; Mariotti, S.; Nieddu, A. et al. (1999). "AKEntAnnos. The Sardinia Study of Extreme Longevity". Aging Clinical and Experimental Research 11 (3): 142–149. doi:10.1007/bf03399655. ISSN 1720-8319. PMID 10476308. http://dx.doi.org/10.1007/bf03399655. 
  5. ↑ Schaeffel, Frank (1999). "Das wachsende Auge - ein optisches System mit Autofokus". Biologie in unserer Zeit 29 (4): 238–246. doi:10.1002/biuz.960290407. ISSN 0045-205X. http://dx.doi.org/10.1002/biuz.960290407. 
  6. ↑ KOMORI, TOYOSUKE (1984). "Looking back of studies on the long life village "Yuzurihara". - Especially upon the relation-ship between long life and bacterial situation in intestine.". Japanese Journal of AMHTS 11 (3): 199–209. doi:10.7143/jhep1975.11.199. ISSN 1884-4081. http://dx.doi.org/10.7143/jhep1975.11.199. 
  7. ↑ Poulain, Michel; Herm, Anne; Pes, Gianni (2013). "The Blue Zones: areas of exceptional longevity around the world". Vienna Yearbook of Population Research 11: 87–108. doi:10.1553/populationyearbook2013s87. ISSN 1728-4414. https://www.jstor.org/stable/43050798. 
  8. ↑ Limited, Media OutReach (2017-02-14). "TimeBlock -- Breakthrough Science-based 'Elixir of Youth' Proven To Reverse Biological Ageing Launches In Singapore" (in en). https://www.globenewswire.com/news-release/2017/02/14/1238533/0/en/TimeBlock-Breakthrough-Science-based-Elixir-of-Youth-Proven-To-Reverse-Biological-Ageing-Launches-In-Singapore.html. 
  9. ↑ Iten, Jocelyne. "Supplementieren: Das Geschäft mit den Schönheitspillen boomt" (in de). https://bellevue.nzz.ch/mode-beauty/supplementieren-das-geschaeft-mit-den-schoenheitspillen-boomt-ld.1629207. 
  10. ↑ "Green Tea Linked To Skin Cell Rejuvenation" (in en). https://www.sciencedaily.com/releases/2003/04/030425071800.htm. 
  11. ↑ "The effects of aging on your skin on MedicineNet.com" (in en). https://www.medicinenet.com/script/main/art.asp?articlekey=43078. 
  12. ↑ "Ethnic Differences in Skin Sensitivity and Responses to Topically Applied Products", Sensitive Skin Syndrome (CRC Press): pp. 71–78, 2006-05-16, doi:10.3109/9781420004601-8, ISBN 978-0-429-12504-1, http://dx.doi.org/10.3109/9781420004601-8, retrieved 2022-01-13 
  13. ↑ "TimeBlock - Plant-based anti-ageing product proven to decrease biological age" (in en-GB). 2017-10-11. https://veritaquantum.com/timeblock/. 
  14. ↑ Lephart, Edwin D. (2013-11-01). "Protective effects of equol and their polyphenolic isomers against dermal aging: Microarray/protein evidence with clinical implications and unique delivery into human skin". Pharmaceutical Biology 51 (11): 1393–1400. doi:10.3109/13880209.2013.793720. ISSN 1388-0209. PMID 23862588. https://doi.org/10.3109/13880209.2013.793720. 
  15. ↑ Lephart, Edwin D. (2016). "Skin aging and oxidative stress: Equol's anti-aging effects via biochemical and molecular mechanisms". Ageing Research Reviews 31: 36–54. doi:10.1016/j.arr.2016.08.001. ISSN 1872-9649. PMID 27521253. https://pubmed.ncbi.nlm.nih.gov/27521253. 
  16. ↑ "AWARDS" (in en). https://www.edphua.com/awards. 




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