Chemistry:L-β-Homoleucine hydrochloride

L-β-Homoleucine hydrochloride

Names
IUPAC name (3S)-3-Amino-5-methylhexanoic acid hydrochloride
Other names H-BETA-HOMOLEU-OH HCL;H-BETA-HOLEU-OH HCL;H-LEU-(C*CH2)OH HCL;L-BETA-HOMOLEUCINE HCL;L-BETA-HOMOLEUCINE HYDROCHLORIDE;(S)-3-AMINO-5-METHYLHEXANOIC ACID HYDROCHLORIDE;L-β-homoleucine.HCI;H-β-homo-Leu-OH
Identifiers
CAS Number	96386-92-4
3D model (JSmol)	Interactive image
Beilstein Reference	8073252
PubChem CID	2761524
CompTox Dashboard (EPA)	DTXSID10375812
InChI Key: NXVYPYHWONGEFQ-RGMNGODLSA-N InChI=1/C7H15NO2.ClH/c1-5(2)3-6(8)4-7(9)10;/h5-6H,3-4,8H2,1-2H3,(H,9,10);1H/t6-;/m0./s1
SMILES CC(C)C[C@@H](CC(=O)O)N.Cl
Properties
Chemical formula	C7H15NO2· HCl
Molar mass	181.66 g mol-1
Boiling point	249.1 °C
log P	0.90
Vapor pressure	0.00744 mmHg
Acidity (pKa)	N/A
Hazards
Main hazards	Flammable
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H315, H319, H335
GHS precautionary statements	P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
NFPA 704 (fire diamond)	0 1 0
Flash point	104.5°C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tracking categories (test):

• SizeSet

L-β-Homoleucine hydrochloride, also known as (3S)-3-Amino-5-methylhexanoic acid hydrochloride belongs to a class of unusual amino acids known as β-Homo amino acids or beta amino acids. The more common α-analogues of these amino acids are present in greater quantities and make up most polypeptides in a cell. β-amino acids however, can also be found in nature and bound to polypeptides, although at a reduced frequency. The hydrochloride is the chloride salt of the amino acid.

Properties

Homolecuine shares many of the same properties as its α-analogue lecuine. Some notable differences include being remarkably stable to metabolism, exhibiting slow microbial degradation, and inherently stable to proteases and peptidases, as well as folding into well-ordered secondary structures consisting of helices, turns, and sheets.