Chemistry:Ornithine oxoglutarate

Ornithine oxoglutarate
	Ornithine (top) and ketoglutaric acid (bottom)
Clinical data
ATC code	A05BA06 (WHO) ;
Identifiers
	IUPAC name 2-Oxopentanedioic acid - L-ornithine (1:1);
CAS Number	34414-83-0 ;
PubChem CID	78866;
ChemSpider	71201;
Chemical and physical data
Formula	C10H18N2O7
Molar mass	278.261 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C(C[C@@H](C(=O)O)N)CN.C(CC(=O)O)C(=O)C(=O)O;
	InChI InChI=1S/C5H12N2O2.C5H6O5/c6-3-1-2-4(7)5(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,6-7H2,(H,8,9);1-2H2,(H,7,8)(H,9,10)/t4-;/m0./s1; Key:SLPUVFBNQHVEEU-WCCKRBBISA-N;
	(verify)

Short description: Chemical compound

Ornithine oxoglutarate (OGO) or ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric acid. It is also used to improve nutritional health in elderly patients.^[1]^[2]

References

↑ "Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients". Nutrition 19 (1): 73–5. January 2003. doi:10.1016/S0899-9007(02)00849-3. PMID 12507647.
↑ "A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects". Age and Ageing 23 (4): 303–6. July 1994. doi:10.1093/ageing/23.4.303. PMID 7976777.

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[1] "Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients". Nutrition 19 (1): 73–5. January 2003. doi:10.1016/S0899-9007(02)00849-3. PMID 12507647.

[2] "A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects". Age and Ageing 23 (4): 303–6. July 1994. doi:10.1093/ageing/23.4.303. PMID 7976777.

[1]

[2]

v t e Bile and liver therapy (A05)
Bile therapy	[[Chemistry:Bile bile acid (Chenodeoxycholic acid]] Cholic acid Ursodeoxycholic acid) Obeticholic acid Nicotinyl methylamide Piprozolin Hymecromone Cyclobutyrol
Liver therapy	Arginine glutamate Silymarin Citiolone Epomediol Ornithine oxoglutarate Tidiacic arginine Glycyrrhizin

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Clinical data

Ornithine (top) and ketoglutaric acid (bottom)
ATC code	A05BA06 (WHO)
Identifiers
IUPAC name 2-Oxopentanedioic acid - L-ornithine (1:1)
CAS Number	34414-83-0^Y
PubChem CID	78866
ChemSpider	71201
Chemical and physical data
Formula	C₁₀H₁₈N₂O₇
Molar mass	278.261 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C(C[C@@H](C(=O)O)N)CN.C(CC(=O)O)C(=O)C(=O)O
InChI InChI=1S/C5H12N2O2.C5H6O5/c6-3-1-2-4(7)5(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,6-7H2,(H,8,9);1-2H2,(H,7,8)(H,9,10)/t4-;/m0./s1 Key:SLPUVFBNQHVEEU-WCCKRBBISA-N
(verify)

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