Chemistry:Relmapirazin
From HandWiki
Short description: Chemical compound
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| Trade names | Lumitrace |
| Other names | MB-120 |
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| Formula | C12H16N6O8 |
| Molar mass | 372.294 g·mol−1 |
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Relmapirazin (MB-120) is an investigational fluorescent tracer that is exclusively excreted renally and is used to measure glomerular filtration rate of the kidneys.[1][2][3][4][5][6][7]
References
- ↑ Dorshow, Richard B.; Shieh, Jeng-Jong; Debreczeny, Martin P. (17 March 2023). "Clinical results from a pilot multi-center study using a novel fluorescent tracer agent for renal function measurement". Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV. pp. 19. doi:10.1117/12.2648541. ISBN 9781510659018.
- ↑ Orieux, Arthur; Samson, Chloé; Pieroni, Laurence; Drouin, Sarah; Dang Van, Simon; Migeon, Tiffany; Frere, Perrine; Brunet, Dorothée et al. (5 June 2023). "Pulmonary hypertension without heart failure causes cardiorenal syndrome in a porcine model" (in en). Scientific Reports 13 (1): 9130. doi:10.1038/s41598-023-36124-1. ISSN 2045-2322. PMID 37277538. Bibcode: 2023NatSR..13.9130O.
- ↑ Jang, Soo M.; Shieh, Jeng-Jong; Riley, Ivan R.; Dorshow, Richard B.; Mueller, Bruce A. (July 2023). "Adsorption and Clearance of the Novel Fluorescent Tracer Agent MB-102 During Continuous Renal Replacement Therapy: In Vitro Results". ASAIO Journal 69 (7): 702–707. doi:10.1097/MAT.0000000000001943. ISSN 1058-2916. PMID 37071749. PMC 10298171. https://journals.lww.com/asaiojournal/fulltext/2023/07000/adsorption_and_clearance_of_the_novel_fluorescent.19.aspx.
- ↑ Rosner, Mitchell H.; Sprangers, Ben; Sandhu, Geeta; Malyszko, Jolanta (November 2022). "Glomerular Filtration Rate Measurement and Chemotherapy Dosing". Seminars in Nephrology 42 (6): 151340. doi:10.1016/j.semnephrol.2023.151340. PMID 37086497.
- ↑ McMahon, Blaithin A.; Rosner, Mitchell H. (February 2020). "GFR Measurement and Chemotherapy Dosing in Patients with Kidney Disease and Cancer". Kidney360 1 (2): 141–150. doi:10.34067/KID.0000952019. PMID 35372903.
- ↑ Schneider, Antoine G.; Molitoris, Bruce A. (December 2020). "Real-time glomerular filtration rate: improving sensitivity, accuracy and prognostic value in acute kidney injury". Current Opinion in Critical Care 26 (6): 549–555. doi:10.1097/MCC.0000000000000770. PMID 33002974.
- ↑ Dorshow, Richard B.; Johnson, James R.; Shieh, Jeng-Jong; Riley, I. Rochelle; Rogers, Thomas E.; Pino, Christopher J.; Johnston, Kimberly A.; Tang, Peter et al. (July 2023). "Transdermal Detection of MB-102 and Correlation to Meropenem Pharmacokinetics During Continuous Renal Replacement Therapy: In Vivo Results". ASAIO Journal 69 (7): 708–715. doi:10.1097/MAT.0000000000001945. PMID 37097973.
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