Chemistry:Cetadiol
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Short description: Chemical compound
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| Other names | Androst-5-ene-3β,16α-diol; 3β,16α-Dihydroxy-5-androstene |
| Routes of administration | Oral |
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| Formula | C19H30O2 |
| Molar mass | 290.447 g·mol−1 |
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Cetadiol, also known as androst-5-ene-3β,16α-diol, is a drug described as a "steroid tranquilizer" which was briefly investigated as a treatment for alcoholism in the 1950s.[1][2][3][4][5] It is an androstane steroid and analogue of 5-androstenediol (androst-5-ene-3β,17β-diol) and 16α-hydroxy-DHEA (androst-5-ene-3β,16α-diol-17-one), but showed no androgenic or myotrophic activity in animal bioassays.[4] The drug was reported in 1956 and studied until 1958.[1]
Chemistry
See also
- Androstadienol (androsta-5,16-dien-3β-ol)
- Androstenol (5α-androst-16-en-3α-ol)
- 4-Androstadienol (PH94B; Aloradine)
- Cyclopregnol
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 86–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA86.
- ↑ Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. 2001. p. 1841. ISBN 978-3-527-30247-5. https://books.google.com/books?id=zmpqAAAAMAAJ.
- ↑ "New steroid hormone tranquilizing agent (cetadiol)". The American Journal of Psychiatry 113 (10): 930. April 1957. doi:10.1176/ajp.113.10.930. PMID 13402989.
- ↑ 4.0 4.1 "Cetadiol (5-androstene-3 16-diol) in the treatment of hospitalized alcoholics". The American Journal of Psychiatry 112 (10): 845. April 1956. doi:10.1176/ajp.112.10.845. PMID 13302491.
- ↑ "The effect of cetadiol on delirium tremens, alcoholic hallucinosis, and alcohol withdrawal". The American Journal of Psychiatry 114 (10): 935–936. April 1958. doi:10.1176/ajp.114.10.935. PMID 13508929.
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