Chemistry:Elafibranor
From HandWiki
Short description: Chemical compound
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| Other names | GFT505, SureCN815512 |
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| Formula | C22H24O4S |
| Molar mass | 384.49 g·mol−1 |
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Elafibranor (INN,[2] code name GFT505) is an experimental medication that is being studied and developed by Genfit for the treatment of cardiometabolic diseases including diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD).[3][4][5]
Elafibranor is a dual PPARα/δ agonist.[6][7]
See also
- MBX-8025
- Resveratrol
- Telmisartan
References
- ↑ "Effects of the new dual PPAR α/δ agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism". Diabetes Care 34 (9): 2008–14. September 2011. doi:10.2337/dc11-0093. PMID 21816979.
- ↑ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 74". World Health Organization. p. 10. https://www.who.int/medicines/publications/druginformation/innlists/74_PrePub_INN_Recommended_List_Report.pdf.
- ↑ "Advanced Compound Status" (Press release). Genfit. Archived from the original on 2013-04-11.
- ↑ "GFT505 Broadens Its Therapeutic Potential" (PDF) (Press release). Archived (PDF) from the original on 10 July 2021. Retrieved 31 Mar 2013.
- ↑ "GFT505 for the treatment of nonalcoholic steatohepatitis and type 2 diabetes". Expert Opinion on Investigational Drugs 23 (10): 1441–8. October 2014. doi:10.1517/13543784.2014.954034. PMID 25164277.
- ↑ US Patent No. 7655641 "96 dpi image of original patent USPTO 7655641". http://www.google.com/patents/US7655641.pdf.
- ↑ Vázquez-Carrera, M. (2012). "GFT-505". Drugs of the Future 37 (8): 555–559. doi:10.1358/dof.2012.037.08.1835977. http://www.biomdl.com/wp-content/uploads/2013/03/GFT505_DrugFut2012.8P555.pdf.[yes|permanent dead link|dead link}}]
External links
- Genfit Pharmaceutical
- NashBiotechs Several articles on drug candidates in NASH
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