Biology:23S rRNA (cytidine2498-2'-O)-methyltransferase

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Short description: Class of enzymes
23S rRNA (cytidine2498-2'-O)-methyltransferase
Identifiers
EC number2.1.1.186
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytidine2498 in 23S rRNA [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 2'-O-methylcytidine2498 in 23S rRNA

References

  1. "YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA". Molecular Microbiology 72 (5): 1147–58. June 2009. doi:10.1111/j.1365-2958.2009.06709.x. PMID 19400805. 

External links