Biology:Trimethylamine-corrinoid protein Co-methyltransferase
From HandWiki
| Trimethylamine-corrinoid protein Co-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.250 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Trimethylamine-corrinoid protein Co-methyltransferase (EC 2.1.1.250, mttB (gene), trimethylamine methyltransferase) is an enzyme with systematic name trimethylamine:5-hydroxybenzimidazolylcobamide Co-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- trimethylamine + [Co(I) trimethylamine-specific corrinoid protein] [math]\displaystyle{ \rightleftharpoons }[/math] [methyl-Co(III) trimethylamine-specific corrinoid protein] + dimethylamine
This enzyme is involved in methanogenesis from trimethylamine.
References
- ↑ "Reconstitution of trimethylamine-dependent coenzyme M methylation with the trimethylamine corrinoid protein and the isozymes of methyltransferase II from Methanosarcina barkeri". Journal of Bacteriology 179 (3): 846–52. February 1997. doi:10.1128/jb.179.3.846-852.1997. PMID 9006042.
- ↑ "Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases". Current Opinion in Chemical Biology 8 (5): 484–91. October 2004. doi:10.1016/j.cbpa.2004.08.012. PMID 15450490.
External links
- Trimethylamine---corrinoid+protein+Co-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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