Chemistry:2,6-Dimethylpiperidine

2,6-Dimethylpiperidine

Names
Preferred IUPAC name 2,6-Dimethylpiperidine
Other names 2,6-Lupetidine; nanofin; nanophyn
Identifiers
CAS Number	504-03-0 N
3D model (JSmol)	Interactive image Interactive image
ChEMBL	ChEMBL2104431
ChemSpider	62076 Y
EC Number	207-981-6
PubChem CID	68843
RTECS number	OK5775000
UNII	329I5805BP
InChI InChI=1S/C7H15N/c1-6-4-3-5-7(2)8-6/h6-8H,3-5H2,1-2H3 Y Key: SDGKUVSVPIIUCF-UHFFFAOYSA-N Y InChI=1/C7H15N/c1-6-4-3-5-7(2)8-6/h6-8H,3-5H2,1-2H3 Key: SDGKUVSVPIIUCF-UHFFFAOYAU
SMILES CC1CCCC(C)N1 N1C(C)CCCC1C
Properties
Chemical formula	C7H15N
Molar mass	113.204 g·mol−1
Appearance	Colorless liquid
Density	0.84 g/mL
Boiling point	113.2 °C (235.8 °F; 386.3 K)
Solubility in water	Low
Solubility in other solvents	Most organic solvents
Basicity (pKb)	ca. 10
Refractive index (nD)	1.4394
Hazards
Main hazards	Flammable
GHS pictograms
GHS Signal word	Danger
GHS hazard statements	H225, H314, H315, H319, H335
GHS precautionary statements	P210, P233, P240, P241, P242, P243, P260, P261, P264, P271, P280, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P310, P312, P321, P332+313, P337+313, P362, P363, P370+378, P403+233
Flash point	11 °C (52 °F; 284 K)
Related compounds
Related compounds	Piperidine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

2,6-Dimethylpiperidines are chemical compounds with the formula C₅H₈(CH₃)₂NH. Three stereoisomers exist: the achiral (R,S)-isomer and the chiral (R,R)/(S,S) enantiomeric pair. Dimethylpiperidines are derivatives of the heterocycle piperidine, wherein two hydrogen atoms are replaced by methyl groups.

The 2,6-dimethylpiperidines are prepared by reduction of 2,6-dimethylpyridine (2,6-lutidine). The achiral isomer is the predominant isomer produced in this reaction.

The 2,6-dimethylpiperidines are of interest for their conformational properties. The (R,S)-isomer exists largely in the chair conformation with equatorial methyl groups. The (R,R)/(S,S)-isomers are attractive chiral secondary amine building blocks.

See also

Compound Summary 2,6-Dimethylpiperidine on National Library of Medicine National Center