Biology:Catechol 2,3-dioxygenase

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Catechol 2,3-dioxygenase
3hpy.jpg
Catechol 2,3-dioxygenase tetramer, Pseudomonas alkylphenolica
Identifiers
EC number1.13.11.2
CAS number9029-46-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Catechol 2,3-dioxygenase (EC 1.13.11.2, 2,3-pyrocatechase, catechol 2,3-oxygenase, catechol oxygenase, metapyrocatechase, pyrocatechol 2,3-dioxygenase) is an enzyme with systematic name catechol:oxygen 2,3-oxidoreductase (decyclizing).[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Degradation of catechol.svg
catechol + O2 [math]\displaystyle{ \rightleftharpoons }[/math] 2-hydroxymuconate semialdehyde

This enzyme contains Fe(II).

References

  1. "Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid". The Biochemical Journal 300 ( Pt 2) (2): 429–36. June 1994. doi:10.1042/bj3000429. PMID 8002948. 
  2. "3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1". Microbiology 140 ( Pt 7) (7): 1713–22. July 1994. doi:10.1099/13500872-140-7-1713. PMID 8075807. 
  3. "Direct oxygenation by O2, oxygenases". The Enzymes. 8 (2nd ed.). New York: Academic Press. 1963. pp. 353–371. 
  4. "Metapyrocatachase: a new catechol-cleaving enzyme". The Journal of Biological Chemistry 236: 2223–8. August 1961. PMID 13757654. 
  5. "Metapyrocatechase. I. Purification, Crystallization and Some Properties". Biochemische Zeitschrift 338: 582–90. 1963. PMID 14087325. 

External links