Biography:Duncan Odom

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Duncan Odom
Born
Duncan T. Odom
Alma mater
Awards
  • Crick Lecture (2014)[1]
  • EMBO Member (2015)[2]
Scientific career
Fields
Institutions
ThesisThe application of metallointercalators in recognition of and charge transport in nucleic acids (2001)
Doctoral advisorJacqueline Barton[5]
Other academic advisorsRichard A. Young[6]
Doctoral studentsChristina Ernst[7]
Websitewww.cruk.cam.ac.uk/users/duncan-odom

Duncan T. Odom is a research group leader at the Cancer Research UK Cambridge Institute (CRUK CI) at the University of Cambridge.[3][6] Previously he was as an associate faculty member at the Wellcome Trust Sanger Institute from 2011 to 2018.[4]

Education

Odom was educated at the New College of Florida where he was awarded a Bachelor of Arts degree in Chemistry in 1995.[4] He continued his study at California Institute of Technology (Caltech) where he was awarded a PhD in chemical engineering for research on DNA-binding metallo-intercalators supervised by Jacqueline Barton.[6][5]

Career and research

After a period as a postdoctoral researcher[8] in genetics and genomics at the Whitehead Institute in Cambridge, Massachusetts with Richard A. Young,[4] he established his research group at the University of Cambridge in 2006.[6] His research investigates how transcription and transcriptional regulation vary during evolution, and its implications for diseases such as cancer, using high throughput biology methods to investigate genome evolution.[9][10][11][12] As of 2017, according to Google Scholar his most highly-cited papers have been published in Cell,[13] Chemical Reviews,[14] and Science.[15][16]

His research has been funded by the National Institute of Diabetes and Digestive and Kidney Diseases,[6] the Alfred P. Sloan Foundation, the European Research Council (ERC),[citation needed] the European Molecular Biology Organization (EMBO), the Wellcome Trust[17] and Cancer Research UK.[6] His former doctoral students include Christina Ernst.[7]

Awards and honours

Odom was awarded the Francis Crick Medal and Lecture in 2014[1][18] for his “pioneering work in the field of comparative functional genomics, which has changed our understanding of the evolution of mammalian transcriptional regulation.”[1] He was awarded EMBO Membership in 2015,[2] and the Mary F. Lyon Medal from The Genetics Society in 2016.[19]

References

  1. ↑ 1.0 1.1 1.2 Anon (2014). "Crick Lecture: Genetic control and the mammalian radiation". London: Royal Society. Archived from the original on 2017-05-03. https://web.archive.org/web/20170503164005/https://royalsociety.org/science-events-and-lectures/2014/francis-crick/. 
  2. ↑ 2.0 2.1 Anon (2015). "Duncan T. Odom". Heidelberg: European Molecular Biology Organization. http://people.embo.org/profile/duncan-t-odom. 
  3. ↑ 3.0 3.1 {{Google Scholar id}} template missing ID and not present in Wikidata.
  4. ↑ 4.0 4.1 4.2 4.3 Anon (2016). "Dr Duncan Odom: Associate Faculty". Wellcome Trust. Archived from the original on 2016-09-07. https://web.archive.org/web/20160907141336/http://www.sanger.ac.uk/people/directory/odom-duncan. 
  5. ↑ 5.0 5.1 Odom, Duncan T. (2001). The application of metallointercalators in recognition of and charge transport in nucleic acids (PhD thesis). California Institute of Technology. OCLC 874759941. ProQuest 251012080.
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Duncan Odom Entry at ORCID
  7. ↑ 7.0 7.1 Ernst, Christina (2018). Transcriptional and developmental consequences of aneuploidy during male meiosis. cam.ac.uk (PhD thesis). University of Cambridge. doi:10.17863/CAM.25556. OCLC 1065352558. EThOS uk.bl.ethos.753466. Free to read
  8. ↑ Odom, Duncan T. (2014). "Survival strategies for choosing the right postdoc position". Genome Biology 15 (3): 107. doi:10.1186/gb4163. PMID 25001498.  open access
  9. ↑ Odom, Duncan (2017). "Odom group: Transcription Regulation Laboratory". Archived from the original on 2017-02-07. https://web.archive.org/web/20170207043900/http://www.cruk.cam.ac.uk/research-groups/odom-group. 
  10. ↑ Villar, Diego; Berthelot, Camille; Aldridge, Sarah; Rayner, Tim F.; Lukk, Margus; Pignatelli, Miguel; Park, Thomas J.; Deaville, Robert et al. (2015). "Enhancer Evolution across 20 Mammalian Species". Cell 160 (3): 554–566. doi:10.1016/j.cell.2015.01.006. ISSN 0092-8674. PMID 25635462. 
  11. ↑ Stefflova, Klara; Thybert, David; Wilson, Michael D.; Streeter, Ian; Aleksic, Jelena; Karagianni, Panagiota; Brazma, Alvis; Adams, David J. et al. (2013). "Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals". Cell 154 (3): 530–540. doi:10.1016/j.cell.2013.07.007. ISSN 0092-8674. PMID 23911320.  open access
  12. ↑ Ernst, Christina; Pike, Jeremy; Aitken, Sarah J; Long, Hannah K; Eling, Nils; Stojic, Lovorka; Ward, Michelle C; Connor, Frances et al. (2016). "Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis". eLife 5. doi:10.7554/eLife.20235. ISSN 2050-084X. PMID 27855777.  open access
  13. ↑ Lee, Tong Ihn; Jenner, Richard G.; Boyer, Laurie A.; Guenther, Matthew G.; Levine, Stuart S.; Kumar, Roshan M.; Chevalier, Brett; Johnstone, Sarah E. et al. (2006). "Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells". Cell 125 (2): 301–313. doi:10.1016/j.cell.2006.02.043. ISSN 0092-8674. PMID 16630818.  open access
  14. ↑ Erkkila, Kathryn E.; Odom, Duncan T.; Barton, Jacqueline K. (1999). "Recognition and Reaction of Metallointercalators with DNA". Chemical Reviews 99 (9): 2777–2796. doi:10.1021/cr9804341. ISSN 0009-2665. PMID 11749500. 
  15. ↑ Lee, T. I. (2002). "Transcriptional Regulatory Networks in Saccharomyces cerevisiae". Science 298 (5594): 799–804. doi:10.1126/science.1075090. ISSN 0036-8075. PMID 12399584. 
  16. ↑ Odom, D. T. (2004). "Control of Pancreas and Liver Gene Expression by HNF Transcription Factors". Science 303 (5662): 1378–1381. doi:10.1126/science.1089769. ISSN 0036-8075. PMID 14988562.  open access
  17. ↑ Anon (2017). "Investigator Awards in Science: people we've funded". Wellcome Trust. Archived from the original on 2017-04-26. https://web.archive.org/web/20170426142635/https://wellcome.ac.uk/what-we-do/directories/investigator-awards-science-people-funded. 
  18. ↑ Event video: Genetic control and the mammalian radiation on YouTube
  19. ↑ "Mary Lyon Medal 2016 - Dr Duncan Odum - Genetics Society". http://www.genetics.org.uk/medals-and-prizes/2015-winners/mary-lyon-medal/mary-lyon-medal-2016-dr-duncan-odum/. Retrieved 28 November 2018. 




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