Biology:(Methyl-Co(III) methanol-specific corrinoid protein):coenzyme M methyltransferase
From HandWiki
Short description: Class of enzymes
| (Methyl-Co(III) methanol-specific corrinoid protein):coenzyme M methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.246 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(Methyl-Co(III) methanol-specific corrinoid protein):coenzyme M methyltransferase (EC 2.1.1.246, methyltransferase 2, mtaA (gene)) is an enzyme with systematic name methylated methanol-specific corrinoid protein:coenzyme M methyltransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M ⇌ methyl-CoM + [Co(I) methanol-specific corrinoid protein]
Free methylcob(I)alamin can substitute for the corrinoid protein in vitro.
References
- ↑ "Methylcobamide:coenzyme M methyltransferase isozymes from Methanosarcina barkeri. Physicochemical characterization, cloning, sequence analysis, and heterologous gene expression". The Journal of Biological Chemistry 271 (31): 18725–31. August 1996. doi:10.1074/jbc.271.31.18725. PMID 8702528.
- ↑ "Methylcobalamin: coenzyme M methyltransferase isoenzymes MtaA and MtbA from Methanosarcina barkeri. Cloning, sequencing and differential transcription of the encoding genes, and functional overexpression of the mtaA gene in Escherichia coli". European Journal of Biochemistry 235 (3): 653–9. February 1996. doi:10.1111/j.1432-1033.1996.00653.x. PMID 8654414.
- ↑ "Methanol:coenzyme M methyltransferase from Methanosarcina barkeri. Zinc dependence and thermodynamics of the methanol:cob(I)alamin methyltransferase reaction". European Journal of Biochemistry 249 (1): 280–5. October 1997. doi:10.1111/j.1432-1033.1997.t01-1-00280.x. PMID 9363780.
- ↑ "Methanol:coenzyme M methyltransferase from Methanosarcina barkeri. Purification, properties and encoding genes of the corrinoid protein MT1". European Journal of Biochemistry 243 (3): 670–7. February 1997. doi:10.1111/j.1432-1033.1997.t01-1-00670.x. PMID 9057830.
- ↑ "Methanol:coenzyme M methyltransferase from Methanosarcina barkeri -- substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin". European Journal of Biochemistry 261 (3): 674–81. May 1999. doi:10.1046/j.1432-1327.1999.00355.x. PMID 10215883.
External links
- (methyl-Co(III)+methanol-specific+corrinoid+protein):coenzyme+M+methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
 |  |
