Biology:16-hydroxysteroid epimerase
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Short description: Class of enzymes
| 16-hydroxysteroid epimerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.1.99.2 | ||||||||
| CAS number | 37318-40-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 16-hydroxysteroid epimerase (EC 5.1.99.2) is an enzyme that catalyzes the chemical reaction
- 16alpha-hydroxysteroid [math]\displaystyle{ \rightleftharpoons }[/math] 16beta-hydroxysteroid
Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 16-hydroxysteroid 16-epimerase.
References
- "[Steroid epimerase--a new enzyme of estrogen metabolism]". Biochim. Biophys. Acta 159 (2): 377–89. 1968. doi:10.1016/0005-2744(68)90086-7. PMID 5657462.
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