Biology:16S rRNA (guanine1207-N2)-methyltransferase
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Short description: Class of enzymes
16S rRNA (guanine1207-N2)-methyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.1.1.172 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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16S rRNA (guanine1207-N2)-methyltransferase (EC 2.1.1.172, m2G1207 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine1207-N2)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine1207 in 16S rRNA [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + N2-methylguanine1207 in 16S rRNA
The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA.
References
- ↑ "Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli". The Journal of Biological Chemistry 274 (2): 924–9. January 1999. doi:10.1074/jbc.274.2.924. PMID 9873033.
- ↑ "Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC". Nucleic Acids Research 35 (13): 4264–74. 2007. doi:10.1093/nar/gkm411. PMID 17576679.
External links
- 16S+rRNA+(guanine1207-N2)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
![]() | Original source: https://en.wikipedia.org/wiki/16S rRNA (guanine1207-N2)-methyltransferase.
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