Biology:16S rRNA (guanine527-N7)-methyltransferase
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Short description: Class of enzymes
| 16S rRNA (guanine527-N7)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.170 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
16S rRNA (guanine527-N7)-methyltransferase (EC 2.1.1.170, ribosomal RNA small subunit methyltransferase G, 16S rRNA methyltransferase RsmG, GidB, rsmG (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine527-N7)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine527 in 16S rRNA [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA
The enzyme specifically methylates guanine527 at N7 in 16S rRNA.
References
- ↑ "Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria". Molecular Microbiology 63 (4): 1096–106. February 2007. doi:10.1111/j.1365-2958.2006.05585.x. PMID 17238915.
- ↑ "Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold". Proteins 47 (4): 563–7. June 2002. doi:10.1002/prot.10121. PMID 12001236.
External links
- 16S+rRNA+(guanine527-N7)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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