Biology:1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase
| 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.6.1.56 | ||||||||
| CAS number | 57127-19-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase (EC 2.6.1.56) is an enzyme that catalyzes the chemical reaction
- 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate [math]\displaystyle{ \rightleftharpoons }[/math] 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine
Thus, the two substrates of this enzyme are 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol and pyruvate, whereas its two products are 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase. Other names in common use include guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase, and L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase.
References
- Walker JB (1971). "Enzymatic reactions involved in streptomycin biosynthesis and metabolism". Lloydia 34 (4): 363–71. PMID 4376579.
- "Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines". Biochemistry 8 (3): 763–70. 1969. doi:10.1021/bi00831a003. PMID 5781017.
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