Biology:2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase
From HandWiki
Short description: Class of enzymes
| 2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.201 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase (EC 2.1.1.201, ubiE (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol 5-C-methyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
This enzyme is involved in ubiquinone biosynthesis.
References
- ↑ "A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene". Journal of Bacteriology 179 (5): 1748–54. March 1997. doi:10.1128/jb.179.5.1748-1754.1997. PMID 9045837.
- ↑ "Characterization and genetic analysis of mutant strains of Escherichia coli K-12 accumulating the biquinone precursors 2-octaprenyl-6-methoxy-1,4-benzoquinone and 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone". Journal of Bacteriology 105 (3): 769–78. March 1971. doi:10.1128/jb.105.3.769-778.1971. PMID 4323297.
- ↑ "The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain". The Journal of Biological Chemistry 272 (14): 9175–81. April 1997. doi:10.1074/jbc.272.14.9175. PMID 9083048.
- ↑ "Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis". The Journal of Biological Chemistry 272 (14): 9182–8. April 1997. doi:10.1074/jbc.272.14.9182. PMID 9083049.
External links
- 2-methoxy-6-polyprenyl-1,4-benzoquinol+methylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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