Biology:23S rRNA (guanine1835-N2)-methyltransferase
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Short description: Class of enzymes
23S rRNA (guanine1835-N2)-methyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.1.1.174 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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23S rRNA (guanine1835-N2)-methyltransferase (EC 2.1.1.174, ygjO (gene), rlmG (gene), ribosomal RNA large subunit methyltransferase G) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine1835 in 23S rRNA [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.
References
- ↑ "Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA". Journal of Molecular Biology 364 (1): 26–31. November 2006. doi:10.1016/j.jmb.2006.09.008. PMID 17010380.
External links
- 23S+rRNA+(guanine1835-N2)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/23S rRNA (guanine1835-N2)-methyltransferase.
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