Biology:ACYP1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
![]() Generic protein structure example |
Acylphosphatase-1 is an enzyme that in humans is encoded by the ACYP1 gene.[1][2][3]
Function
Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis.[3]
References
- ↑ "Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase". FEBS Letters 367 (2): 145–8. Jun 1995. doi:10.1016/0014-5793(95)00553-L. PMID 7796909.
- ↑ "Assignment of the human erythrocyte acylphosphatase gene (ACYP1) to chromosome band 14q24.3". Cytogenetics and Cell Genetics 81 (3–4): 235–6. Oct 1998. doi:10.1159/000015037. PMID 9730610.
- ↑ 3.0 3.1 "Entrez Gene: ACYP1 acylphosphatase 1, erythrocyte (common) type". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=97.
External links
- Human ACYP1 genome location and ACYP1 gene details page in the UCSC Genome Browser.
Further reading
- "Effects of acylphosphatase on the activity of erythrocyte membrane Ca2+ pump". The Journal of Biological Chemistry 266 (17): 10867–71. Jun 1991. doi:10.1016/S0021-9258(18)99099-X. PMID 1645713.
- "Immunoaffinity purification and immunoassay determination of human erythrocyte acylphosphatase". Biotechnology and Applied Biochemistry 12 (4): 450–9. Aug 1990. doi:10.1111/j.1470-8744.1990.tb00112.x. PMID 2169259.
- "A new acylphosphatase isoenzyme from human erythrocytes: purification, characterization, and primary structure". Biochemistry 25 (24): 8089–94. Dec 1986. doi:10.1021/bi00372a044. PMID 3026468.
- "A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase". The Journal of Biological Chemistry 278 (1): 194–9. Jan 2003. doi:10.1074/jbc.M206918200. PMID 12409302. https://flore.unifi.it/bitstream/2158/312459/1/paoli%202003.pdf.
- "ACYP1 gene possesses two alternative splicing forms that induce apoptosis". IUBMB Life 56 (1): 29–33. Jan 2004. doi:10.1080/15216540310001654349. PMID 14992377.
![]() | Original source: https://en.wikipedia.org/wiki/ACYP1.
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