Biology:ALDH1B1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene.[1][2]
Function
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.[2]
References
- ↑ "Cloning and characterization of a new functional human aldehyde dehydrogenase gene". The Journal of Biological Chemistry 266 (19): 12257–65. Jul 1991. doi:10.1016/S0021-9258(18)98890-3. PMID 2061311.
- ↑ 2.0 2.1 "Entrez Gene: ALDH1B1 aldehyde dehydrogenase 1 family, member B1". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=219.
External links
- Human ALDH1B1 genome location and ALDH1B1 gene details page in the UCSC Genome Browser.
Further reading
- "Molecular genetics of human aldehyde dehydrogenase". Pharmacogenetics 2 (4): 139–47. Aug 1992. doi:10.1097/00008571-199208000-00001. PMID 1306115.
- "Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13". Genomics 25 (1): 323–5. Jan 1995. doi:10.1016/0888-7543(95)80150-K. PMID 7774944.
- "The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme". Biochemical and Biophysical Research Communications 211 (1): 144–51. Jun 1995. doi:10.1006/bbrc.1995.1789. PMID 7779080.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. Jan 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Diverse polymorphism within a short coding region of the human aldehyde dehydrogenase-5 (ALDH5) gene". Human Genetics 92 (5): 477–80. Nov 1993. doi:10.1007/BF00216454. PMID 8244338.
- "Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues". Journal of Investigative Medicine 44 (2): 42–6. Feb 1996. PMID 8689400.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. Oct 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Intrinsic retinoic acid receptor alpha-cyclin-dependent kinase-activating kinase signaling involves coordination of the restricted proliferation and granulocytic differentiation of human hematopoietic stem cells". Stem Cells 25 (10): 2628–37. Oct 2007. doi:10.1634/stemcells.2007-0264. PMID 17628022.
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