Biology:Acetylacetone-cleaving enzyme

From HandWiki
Short description: Class of enzymes
Acetylacetone-cleaving enzyme
Identifiers
EC number1.13.11.50
CAS number524047-53-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

In enzymology, an acetylacetone-cleaving enzyme (EC 1.13.11.50) is an enzyme that catalyzes the chemical reaction

pentane-2,4-dione + O2 [math]\displaystyle{ \rightleftharpoons }[/math] acetate + 2-oxopropanal

Thus, the two substrates of this enzyme are pentane-2,4-dione and O2, whereas its two products are acetate and 2-oxopropanal.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is acetylacetone:oxygen oxidoreductase. Other names in common use include Dke1, acetylacetone dioxygenase, diketone cleaving dioxygenase, and diketone cleaving enzyme.

References