Biology:AdoMet MTase
From HandWiki
Short description: Protein domain and superfamily
| AdoMet_MTase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | AdoMet_MTase | ||||||||
| Pfam | PF07757 | ||||||||
| Pfam clan | CL0063 | ||||||||
| InterPro | IPR011671 | ||||||||
| |||||||||
S-adenosylmethionine-dependent methyltransferase (SAM-MTase or AdoMet-MTase) is a conserved protein domain and protein superfamily.[1] SAM-MTase proteins are methyltransferases.[2] There are five protein families within SAM-MTase, the largest being class 1.[3]
SAM-MTases use S-adenosyl-L-methionine as a substrate for methylation, creating the product S-adenosyl-L-homocysteine.[3]
References
- ↑ Wang, Jiyao; Chitsaz, Farideh; Derbyshire, Myra K.; Gonzales, Noreen R.; Gwadz, Marc; Lu, Shennan; Marchler, Gabriele H.; Song, James S. et al. (2023-01-06). "The conserved domain database in 2023". Nucleic Acids Research 51 (D1): D384–D388. doi:10.1093/nar/gkac1096. ISSN 1362-4962. PMID 36477806.
- ↑ "DUF1613 is a novel family of eucaryotic AdoMet-dependent methyltransferases". Cell Cycle 5 (14): 1580–2. July 2006. doi:10.4161/cc.5.14.2978. PMID 16861910.
- ↑ 3.0 3.1 "CDD Conserved Protein Domain Family: AdoMet_MTases". https://www.ncbi.nlm.nih.gov/Structure/cdd/cl17173.
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