Biology:ArgJ protein family

From HandWiki
ArgJ
PDB 1vz7 EBI.jpg
ornithine acetyltransferase (orf6 gene product - clavulanic acid biosynthesis) from streptomyces clavuligerus
Identifiers
SymbolArgJ
PfamPF01960
InterProIPR002813
CDDcd02152

In molecular biology, members of the ArgJ protein family are bifunctional protein that catalyses the first (EC 2.3.1.35) and fifth steps (EC 2.3.1.1) in arginine biosynthesis.[1] The structure has been determined for glutamate N-acetyltransferase 2 (ornithine acetyltransferase), an ArgJ-like protein from Streptomyces clavuligerus.[2]

References

  1. "Primary structure, partial purification and regulation of key enzymes of the acetyl cycle of arginine biosynthesis in Bacillus stearothermophilus: dual function of ornithine acetyltransferase". J. Gen. Microbiol. 139 (3): 393–402. March 1993. doi:10.1099/00221287-139-3-393. PMID 8473852. 
  2. "X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster". Biochem. J. 385 (Pt 2): 565–73. January 2005. doi:10.1042/BJ20040814. PMID 15352873. 
This article incorporates text from the public domain Pfam and InterPro: IPR002813