Biology:CYB5R1
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
NADH-cytochrome b5 reductase 1 is an enzyme that in humans is encoded by the CYB5R1 gene.[1][2][3]
Structure
The CYB5R1 gene is located on the 1st chromosome, with its specific location being 1q32.1. The gene contains 9 exons.[3] CYB5R1 encodes a 34.1 kDa protein that is composed of 305 amino acids; 56 peptides have been observed through mass spectrometry data.[4][5]
References
- ↑ "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research 13 (10): 2265–70. Oct 2003. doi:10.1101/gr.1293003. PMID 12975309.
- ↑ "Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells". Proceedings of the National Academy of Sciences of the United States of America 96 (26): 14742–7. Dec 1999. doi:10.1073/pnas.96.26.14742. PMID 10611283. Bibcode: 1999PNAS...9614742Z.
- ↑ 3.0 3.1 "Entrez Gene: CYB5R1 cytochrome b5 reductase 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51706.
- ↑ "Integration of cardiac proteome biology and medicine by a specialized knowledgebase". Circulation Research 113 (9): 1043–53. Oct 2013. doi:10.1161/CIRCRESAHA.113.301151. PMID 23965338.
- ↑ "NADH-cytochrome b5 reductase 1". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=QQ9UHQ9.[yes|permanent dead link|dead link}}]
External links
- Human CYB5R1 genome location and CYB5R1 gene details page in the UCSC Genome Browser.
Further reading
- "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research 12 (2): 117–26. 2007. doi:10.1093/dnares/12.2.117. PMID 16303743.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The influence of mutation at Glu44 and Glu56 of cytochrome b5 on the protein's stabilization and interaction between cytochrome c and cytochrome b5". Biochemistry 37 (40): 14137–50. Oct 1998. doi:10.1021/bi9805036. PMID 9760250.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. Oct 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. Jan 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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