Biology:Chlamydia abortus

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Short description: Species of bacterium
Warning notice about C. abortus on a live stock pen.

Chlamydia abortus
Scientific classification edit
Domain: Bacteria
Phylum: Chlamydiota
Class: Chlamydiia
Order: Chlamydiales
Family: Chlamydiaceae
Genus: Chlamydia
Species:
C. abortus
Binomial name
Chlamydia abortus
Everett et al. 1999

Chlamydia abortus is a species in Chlamydiota that causes abortion and fetal death in mammals, including humans. Chlamydia abortus was renamed in 1999 as Chlamydophila psittaci along with all Chlamydiota except Chlamydia trachomatis. This was based on a lack of evident glycogen production and on resistance to the antibiotic sulfadiazine. In 1999 C. psittaci and C. abortus were recognized as distinct species based on differences of pathogenicity and DNA–DNA hybridization.[1] In 2015, this new name was reverted to Chlamydia.

In humans

There are approximately one or two cases of chlamydiosis diagnosis in pregnant women in the United Kingdom per year. Typically transmission occurs from contact with livestock who have recently given birth. The true prevalence in humans is unknown because serological antibody tests are unable to distinguish between C. abortus and other more common species such as Chlamydia trachomatis.[2]

In other animals

Chlamydia abortus is endemic among ruminants such as cows and sheep and has been associated with abortion in a horse, a rabbit, guinea pigs, mice, pigs and humans. Infected females shed bacteria near the time of ovulation, so C. abortus is transmitted orally and sexually among mammals. All C. abortus strains were isolated or PCR-amplified from the placenta or fetal organs after spontaneous abortion. C. abortus infection generally remains unapparent until an animal aborts late in gestation or gives birth to a weak or dead fetus.

Chlamydia abortus has been isolated from birds.

Genome structure

Chlamydia abortus has a relatively small genome that contains 1.14 Mbp with 961 protein coding genes.[3]

References

Further reading

  • Chen, Qiwei; Gong, Xiaowei; Zheng, Fuying; Cao, Xiaoan; Li, Zhaocai; Zhou, Jizhang (2014). "Seroprevalence of Chlamydophila abortus infection in yaks (Bos grunniens) in Qinghai, China". Tropical Animal Health and Production 46 (3): 503–507. doi:10.1007/s11250-013-0519-8. PMID 24343703. 
  • Longbottom, D; Livingstone, M (March 2006). "Vaccination Against Chlamydial Infections of Man and Animals". The Veterinary Journal 171 (2): 263–275. doi:10.1016/j.tvjl.2004.09.006. PMID 16490708. 

Wikidata ☰ Q2705361 entry