Biology:DUSP15
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Dual specificity protein phosphatase 15 is an enzyme that in humans is encoded by the DUSP15 gene.[1][2]
The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phosphatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants, encoding two different isoforms have been found for this gene.[2]
References
- ↑ "VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX". J Biol Chem 279 (31): 32586–91. Jul 2004. doi:10.1074/jbc.M403442200. PMID 15138252.
- ↑ 2.0 2.1 "Entrez Gene: DUSP15 dual specificity phosphatase 15". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=128853.
Further reading
- "Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase.". Proteins 61 (3): 694–7. 2006. doi:10.1002/prot.20642. PMID 16170801.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. 2002. doi:10.1038/414865a. PMID 11780052. Bibcode: 2001Natur.414..865D.
- "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. 2000. doi:10.1073/pnas.97.7.3491. PMID 10737800. Bibcode: 2000PNAS...97.3491D.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Dual specificity protein phosphatase 15
PDB gallery | |
|---|---|
|
 |  |
