Biology:Geranyl diphosphate 2-C-methyltransferase
From HandWiki
Short description: Class of enzymes
| Geranyl diphosphate 2-C-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.255 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Geranyl diphosphate 2-C-methyltransferase (EC 2.1.1.255, SCO7701, GPP methyltransferase, GPPMT, 2-methyl-GPP synthase, MGPPS, geranyl pyrophosphate methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:geranyl-diphosphate 2-C-methyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + geranyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate
This enzyme takes part in synthesis of 2-methylisoborneol.
References
- ↑ "Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor". Journal of the American Chemical Society 130 (28): 8908–9. July 2008. doi:10.1021/ja803639g. PMID 18563898.
- ↑ "Crystallization and preliminary X-ray crystallographic study of a methyltransferase involved in 2-methylisoborneol biosynthesis in Streptomyces lasaliensis". Acta Crystallographica Section F 67 (Pt 3): 417–20. March 2011. doi:10.1107/s1744309110051523. PMID 21393856.
- ↑ "Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol". Proceedings of the National Academy of Sciences of the United States of America 105 (21): 7422–7. May 2008. doi:10.1073/pnas.0802312105. PMID 18492804.
- ↑ "Biosynthesis of 2-methylisoborneol in cyanobacteria". Environmental Science & Technology 45 (3): 992–8. February 2011. doi:10.1021/es102992p. PMID 21174459.
External links
- Geranyl+diphosphate+2-C-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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