Biology:HYMAI
From HandWiki
In molecular biology, Hydatidiform mole associated and imprinted (non-protein coding), also known as HYMAI, is a long non-coding RNA. It is an imprinted gene, which is paternally expressed.[1] Overexpression of HYMAI and the protein-coding gene PLAG1 causes transient neonatal diabetes mellitus type 1 (TNDM1).[2]
See also
- Long noncoding RNA
References
- ↑ "A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC.". Genomics 67 (3): 248–255. 2000. doi:10.1006/geno.2000.6266. PMID 10936046. https://pubmed.ncbi.nlm.nih.gov/10936046.
- ↑ "Transient neonatal diabetes mellitus type 1.". Am J Med Genet C Semin Med Genet 154C (3): 335–342. 2010. doi:10.1002/ajmg.c.30272. PMID 20803656.
Further reading
- "The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice.". Genomics 88 (5): 650–658. 2006. doi:10.1016/j.ygeno.2006.07.005. PMID 16928428.
- "Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach.". Diabetes 55 (8): 2272–2276. 2006. doi:10.2337/db06-0216. PMID 16873690.
- "Establishment of the primary imprint of the HYMAI/PLAGL1 imprint control region during oogenesis.". Cytogenet Genome Res 113 (1–4): 247–252. 2006. doi:10.1159/000090839. PMID 16575187. https://pubmed.ncbi.nlm.nih.gov/16575187.
 |  |
