Biology:L-lysine oxidase
From HandWiki
| L-lysine oxidase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.4.3.14 | ||||||||
| CAS number | 70132-14-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a L-lysine oxidase (EC 1.4.3.14) is an enzyme that catalyzes the chemical reaction
- L-lysine + O2 + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 6-amino-2-oxohexanoate + NH3 + H2O2
The 3 substrates of this enzyme are L-lysine, O2, and H2O, whereas its 3 products are 6-amino-2-oxohexanoate, NH3, and H2O2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is L-lysine:oxygen 2-oxidoreductase (deaminating). Other names in common use include L-lysine alpha-oxidase, and L-lysyl-alpha-oxidase. This enzyme participates in lysine degradation.
References
- "A new antitumor enzyme, L-lysine alpha-oxidase from Trichoderma viride. Purification and enzymological properties". J. Biol. Chem. 255 (3): 976–81. 1980. PMID 6101334.
- Lukasheva, EV; Berezov, TT (October 2002). "L-Lysine alpha-oxidase: physicochemical and biological properties". Biochemistry (Moscow) 67 (10): 1152–8. PMID 12460113.
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