Biology:MYCBP2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Probable E3 ubiquitin-protein ligase MYCBP2 also known as myc-binding protein 2 or protein associates with myc (PAM) is an enzyme that in humans is encoded by the MYCBP2 gene.[1][2]
Structure
PAM contains a N-terminal leucine zipper, central MYC-binding, and C-terminal histone-binding protein homology domains.[1]
Interactions
MYCBP2 has been shown to interact with Myc.[1]
References
- ↑ 1.0 1.1 1.2 "Identification of a large Myc-binding protein that contains RCC1-like repeats". Proc. Natl. Acad. Sci. U.S.A. 95 (16): 9172–7. Sep 1998. doi:10.1073/pnas.95.16.9172. PMID 9689053. Bibcode: 1998PNAS...95.9172G.
- ↑ "Entrez Gene: MYCBP2 MYC binding protein 2". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=23077.
Further reading
- "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. 2002. doi:10.1093/dnares/9.3.99. PMID 12168954.
- "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. 1998. doi:10.1093/dnares/5.6.355. PMID 10048485.
- "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. 2000. doi:10.1101/gr.140200. PMID 11042152.
- "Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex". J. Biol. Chem. 279 (2): 1351–8. 2004. doi:10.1074/jbc.M310208200. PMID 14559897.
- "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. 2004. doi:10.1038/nbt971. PMID 15146197.
- "PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate". EMBO J. 23 (15): 3031–40. 2004. doi:10.1038/sj.emboj.7600321. PMID 15257286.
- "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. 2004. doi:10.1073/pnas.0404720101. PMID 15302935. Bibcode: 2004PNAS..10112130B.
- "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. 2004. doi:10.1016/j.cub.2004.07.051. PMID 15324660. Bibcode: 2004CBio...14.1436J.
- "Histidine residues 912 and 913 in protein associated with Myc are necessary for the inhibition of adenylyl cyclase activity". Mol. Pharmacol. 67 (1): 42–9. 2005. doi:10.1124/mol.104.005355. PMID 15470080.
- "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics 4 (6): 785–95. 2005. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
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