Biology:Methylamine-corrinoid protein Co-methyltransferase
From HandWiki
| Methylamine-corrinoid protein Co-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.248 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Methylamine-corrinoid protein Co-methyltransferase (EC 2.1.1.248, mtmB (gene), monomethylamine methyltransferase) is an enzyme with systematic name monomethylamine:5-hydroxybenzimidazolylcobamide Co-methyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- methylamine + [Co(I) methylamine-specific corrinoid protein] [math]\displaystyle{ \rightleftharpoons }[/math] [methyl-Co(III) methylamine-specific corrinoid protein] + ammonia
This enzyme is involved in methanogenesis from methylamine.
References
- ↑ "Reconstitution of Monomethylamine:Coenzyme M methyl transfer with a corrinoid protein and two methyltransferases purified from Methanosarcina barkeri". The Journal of Biological Chemistry 272 (26): 16570–7. June 1997. doi:10.1074/jbc.272.26.16570. PMID 9195968.
- ↑ "Clustered genes encoding the methyltransferases of methanogenesis from monomethylamine". Journal of Bacteriology 180 (13): 3432–40. July 1998. PMID 9642198.
- ↑ "Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases". Current Opinion in Chemical Biology 8 (5): 484–91. October 2004. doi:10.1016/j.cbpa.2004.08.012. PMID 15450490.
External links
- Methylamine---corrinoid+protein+Co-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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