Biology:Methylamine dehydrogenase (amicyanin)
From HandWiki
| Methylamine dehydrogenase (amicyanin) | |||||||||
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| Identifiers | |||||||||
| EC number | 1.4.9.1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Methylamine dehydrogenase (amicyanin) (EC 1.4.9.1, amine dehydrogenase, primary-amine dehydrogenase) is an enzyme with systematic name methylamine:amicyanin oxidoreductase (deaminating).[1][2][3][4][5] This enzyme catalyses the following chemical reaction:
- methylamine + H2O + amicyanin [math]\displaystyle{ \rightleftharpoons }[/math] formaldehyde + ammonia + reduced amicyanin
This enzyme contains tryptophan tryptophylquinone (TTQ) co-factor.
References
- ↑ "The prosthetic group of methylamine dehydrogenase from Pseudomonas AM1: evidence for a quinone structure". Biochimica et Biophysica Acta 622 (2): 370–4. April 1980. doi:10.1016/0005-2795(80)90050-1. PMID 6246962.
- ↑ "Purification and properties of an amine dehydrogenase from Pseudomonas AM1 and its role in growth on methylamine". The Biochemical Journal 106 (1): 245–55. January 1968. doi:10.1042/bj1060245. PMID 4388687.
- ↑ "Microbial oxidation of amines. Spectral and kinetic properties of the primary amine dehydrogenase of Pseudomonas AM1". The Biochemical Journal 123 (5): 757–71. August 1971. doi:10.1042/bj1230757. PMID 5124384.
- ↑ "Structural comparison of crystal and solution states of the 138 kDa complex of methylamine dehydrogenase and amicyanin from Paracoccus versutus". Biochemistry 47 (25): 6560–70. June 2008. doi:10.1021/bi7023749. PMID 18512962. https://figshare.com/articles/journal_contribution/2857966.
- ↑ "Amicyanin transfers electrons from methylamine dehydrogenase to cytochrome c-551i via a ping-pong mechanism, not a ternary complex". Journal of the American Chemical Society 132 (41): 14537–45. October 2010. doi:10.1021/ja105498m. PMID 20873742.
External links
- Methylamine+dehydrogenase+(amicyanin) at the US National Library of Medicine Medical Subject Headings (MeSH)
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