Biology:Simple Modular Architecture Research Tool
From HandWiki
Short description: Biological database
| Content | |
|---|---|
| Description | Identification scheme for protein domains. |
| Data types captured | Protein domains |
| Organisms | all |
| Contact | |
| Research centre | European Molecular Biology Laboratory |
| Primary citation | PMID 18978020 |
| Access | |
| Website | http://smart.embl-heidelberg.de |
| Miscellaneous | |
| Software license | Free to academics, but not commercial users |
| Version | 7 |
| Curation policy | Yes |
Simple Modular Architecture Research Tool (SMART) is a biological database that is used in the identification and analysis of protein domains within protein sequences.[1][2] SMART uses profile-hidden Markov models built from multiple sequence alignments to detect protein domains in protein sequences. The most recent release of SMART contains 1,204 domain models.[3] Data from SMART was used in creating the Conserved Domain Database collection and is also distributed as part of the InterPro database.[4] The database is hosted by the European Molecular Biology Laboratory in Heidelberg.
References
- ↑ "SMART, a simple modular architecture research tool: identification of signaling domains". Proc. Natl. Acad. Sci. U.S.A. 95 (11): 5857–64. May 1998. doi:10.1073/pnas.95.11.5857. PMID 9600884. PMC 34487. Bibcode: 1998PNAS...95.5857S. http://www.pnas.org/content/95/11/5857.full.pdf.
- ↑ "SMART 6: recent updates and new developments". Nucleic Acids Res. 37 (Database issue): D229–32. January 2009. doi:10.1093/nar/gkn808. PMID 18978020.
- ↑ Letunic, Ivica; Doerks, Tobias; Bork, Peer (January 2015). "SMART: recent updates, new developments and status in 2015". Nucleic Acids Research 43 (Database issue): D257–260. doi:10.1093/nar/gku949. ISSN 1362-4962. PMID 25300481.
- ↑ "InterPro: an integrated documentation resource for protein families, domains and functional sites". Brief. Bioinformatics 3 (3): 225–35. September 2002. doi:10.1093/bib/3.3.225. PMID 12230031.
External links
 |  |
