Biology:Stomoxyn
From HandWiki
| Stomoxyn | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Stomoxyn | ||||||||
| Pfam | PF11585 | ||||||||
| InterPro | IPR021037 | ||||||||
| OPM superfamily | 151 | ||||||||
| OPM protein | 1zrv | ||||||||
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Stomoxyn is an insect antimicrobial peptide localised in the gut epithelium, which functions in killing a range of microorganisms, parasites and some viruses. In water, stomoxyn has a flexible random coil in structure, while in trifluoroethanol it adopts a stable helical structure. Structural similarities to the antimicrobial peptide cecropin A from Hyalophora cecropia suggest that it may function in a similar manner by disrupting the bacterial membrane.[1]
References
- ↑ "Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation". Biopolymers 81 (2): 92–103. February 2006. doi:10.1002/bip.20370. PMID 16170803.
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