Biology:TIMM9
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 Generic protein structure example |
Mitochondrial import inner membrane translocase subunit Tim9 is an enzyme that in humans is encoded by the TIMM9 gene.[1][2][3]
TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space.
These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM][3]
References
- ↑ "The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins". Genomics 61 (3): 259–67. Feb 2000. doi:10.1006/geno.1999.5966. PMID 10552927.
- ↑ "Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria". J Biol Chem 279 (14): 13540–6. Mar 2004. doi:10.1074/jbc.M312485200. PMID 14726512.
- ↑ 3.0 3.1 "Entrez Gene: TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26520.
Further reading
- "Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller". Mol. Cell 21 (1): 123–33. 2006. doi:10.1016/j.molcel.2005.11.010. PMID 16387659.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Assembly of Tim9 and Tim10 into a functional chaperone". J. Biol. Chem. 277 (39): 36100–8. 2002. doi:10.1074/jbc.M202310200. PMID 12138093.
- "Role of the deafness dystonia peptide 1 (DDP1) in import of human Tim23 into the inner membrane of mitochondria". J. Biol. Chem. 276 (40): 37327–34. 2001. doi:10.1074/jbc.M105313200. PMID 11489896.
- "The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom". FEBS Lett. 464 (1–2): 41–7. 2000. doi:10.1016/S0014-5793(99)01665-8. PMID 10611480.
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