Biology:Trigeminal nerve stimulation

From HandWiki

Trigeminal nerve stimulation (TNS) or external Trigenimal nerve stimulation (eTNS) is a non-invasive, non-medication therapy for Attention deficit hyperactivity disorder approved in the United States by the FDA for the treatment of ADHD in children ages 7–12.[1][2][3] It is also used off-label to treat ADHD in adults.[4] External trigeminal nerve stimulation (eTNS) is similar to transcutaneous electrical nerve stimulation (TENS), a treatment for chronic pain. A small device supplies electricity to electrodes that are placed on the skin. The device is able to modulate the intensity and frequency of electrical impulses delivered to the nerve endings in the skin.

There is ongoing investigation and research into the use of trigeminal nerve stimulation to treat other psychiatric disorders, such as depression and PTSD.[5][6]

References

  1. Commissioner, Office of the (2020-03-24). "FDA permits marketing of first medical device for treatment of ADHD" (in en). https://www.fda.gov/news-events/press-announcements/fda-permits-marketing-first-medical-device-treatment-adhd. 
  2. McGough, J. J.; Sturm, A.; Cowen, J.; Tung, K.; Salgari, G. C.; Leuchter, A. F.; Cook, I. A.; Sugar, C. A. et al. (2019). "Double-Blind, Sham-Controlled, Pilot Study of Trigeminal Nerve Stimulation for Attention-Deficit/Hyperactivity Disorder". Journal of the American Academy of Child and Adolescent Psychiatry 58 (4): 403–411.e3. doi:10.1016/j.jaac.2018.11.013. PMID 30768393. 
  3. Greenbaum, Zara (2019-08-01). "A new device for treating ADHD in children". https://www.apa.org/monitor/2019/07-08/adhd-children. 
  4. "Monarch eTNS" (in en). https://www.fermata.health/etns. 
  5. Cook, I. A.; Abrams, M.; Leuchter, A. F. (2016). "Trigeminal Nerve Stimulation for Comorbid Posttraumatic Stress Disorder and Major Depressive Disorder". Neuromodulation 19 (3): 299–305. doi:10.1111/ner.12399. PMID 26818103. 
  6. Powell, Keren; Lin, Kanheng; Tambo, Willians; Saavedra, Andrea Palomo; Sciubba, Daniel; Al Abed, Yousef; Li, Chunyan (2023-12-13). "Trigeminal nerve stimulation: a current state-of-the-art review". Bioelectronic Medicine 9 (1): 30. doi:10.1186/s42234-023-00128-z. ISSN 2332-8886. PMID 38087375.